Independent requirements for Hedgehog signaling by both the anterior heart field and neural crest cells for outflow tract development.
about
Pulling on my heartstrings: mechanotransduction in cardiac development and functionThe primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiationLoss of glypican-3 function causes growth factor-dependent defects in cardiac and coronary vascular developmentTbx3 is required for outflow tract developmentBeta-catenin deficiency causes DiGeorge syndrome-like phenotypes through regulation of Tbx1.A retinoic acid responsive Hoxa3 transgene expressed in embryonic pharyngeal endoderm, cardiac neural crest and a subdomain of the second heart field.BMP signaling modulates hedgehog-induced secondary heart field proliferation.Hedgehog signaling plays a cell-autonomous role in maximizing cardiac developmental potentialN-cadherin prevents the premature differentiation of anterior heart field progenitors in the pharyngeal mesodermal microenvironmentVangl2-regulated polarisation of second heart field-derived cells is required for outflow tract lengthening during cardiac development.Heparan sulfate expression in the neural crest is essential for mouse cardiogenesis.Génie: literature-based gene prioritization at multi genomic scalePax3 is essential for normal cardiac neural crest morphogenesis but is not required during migration nor outflow tract septation.Loss of Wnt5a disrupts second heart field cell deployment and may contribute to OFT malformations in DiGeorge syndromeA Sonic hedgehog (Shh) response deficit in trisomic cells may be a common denominator for multiple features of Down syndromeMesodermal Nkx2.5 is necessary and sufficient for early second heart field developmentConditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignmentBRG1 interacts with GLI2 and binds Mef2c gene in a hedgehog signalling dependent manner during in vitro cardiomyogenesisNumb family proteins: novel players in cardiac morphogenesis and cardiac progenitor cell differentiation.Convergent evolutionary reduction of atrial septation in lungless salamandersPartitioning the heart: mechanisms of cardiac septation and valve developmentIdentification of a Tbx1/Tbx2/Tbx3 genetic pathway governing pharyngeal and arterial pole morphogenesis22q11 Gene dosage establishes an adaptive range for sonic hedgehog and retinoic acid signaling during early development.In vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regeneration.Multiple essential roles for primary cilia in heart development.Gene network and familial analyses uncover a gene network involving Tbx5/Osr1/Pcsk6 interaction in the second heart field for atrial septation.Sonic Hedgehog Signaling and VACTERL Association.High-resolution magnetic resonance histology of the embryonic and neonatal mouse: a 4D atlas and morphologic database.Wnt/β-catenin and sonic hedgehog pathways interact in the regulation of the development of the dorsal mesenchymal protrusion.Notochordal and foregut abnormalities correlate with elevated neural crest apoptosis in Patch embryos.The Dorsal Mesenchymal Protrusion and the Pathogenesis of Atrioventricular Septal Defects.The role of secondary heart field in cardiac development.Primary cilia and organogenesis: is Hedgehog the only sculptor?Islet1-expressing cardiac progenitor cells: a comparison across species.The pathogenesis of atrial and atrioventricular septal defects with special emphasis on the role of the dorsal mesenchymal protrusion.A molecular and genetic outline of cardiac morphogenesis.Jarid2 is among a set of genes differentially regulated by Nkx2.5 during outflow tract morphogenesis.LRP2, an auxiliary receptor that controls sonic hedgehog signaling in development and disease.Targeting the hedgehog signaling pathway for cardiac repair and regeneration.Cardiac outflow tract development relies on the complex function of Sox4 and Sox11 in multiple cell types.
P2860
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P2860
Independent requirements for Hedgehog signaling by both the anterior heart field and neural crest cells for outflow tract development.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Independent requirements for H ...... for outflow tract development.
@en
Independent requirements for H ...... for outflow tract development.
@nl
type
label
Independent requirements for H ...... for outflow tract development.
@en
Independent requirements for H ...... for outflow tract development.
@nl
prefLabel
Independent requirements for H ...... for outflow tract development.
@en
Independent requirements for H ...... for outflow tract development.
@nl
P2093
P356
P1433
P1476
Independent requirements for H ...... for outflow tract development.
@en
P2093
Erik N Meyers
John Klingensmith
Matthew M Goddeeris
Robert Schwartz
P304
P356
10.1242/DEV.02824
P407
P577
2007-03-07T00:00:00Z