Further Exploring Solvent-Exposed Tolerant Regions of Allosteric Binding Pocket for Novel HIV-1 NNRTIs Discovery.

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Further Exploring Solvent-Exposed Tolerant Regions of Allosteric Binding Pocket for Novel HIV-1 NNRTIs Discovery.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

@zh-cn

2018年学术文章

@zh-hans

2018年学术文章

@zh-my

2018年学术文章

@zh-sg

2018年學術文章

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2018年學術文章

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name

Further Exploring Solvent-Expo ...... Novel HIV-1 NNRTIs Discovery.

@en

Further Exploring Solvent-Expo ...... Novel HIV-1 NNRTIs Discovery.

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Item

label

Further Exploring Solvent-Expo ...... Novel HIV-1 NNRTIs Discovery.

@en

Further Exploring Solvent-Expo ...... Novel HIV-1 NNRTIs Discovery.

@nl

prefLabel

Further Exploring Solvent-Expo ...... Novel HIV-1 NNRTIs Discovery.

@en

Further Exploring Solvent-Expo ...... Novel HIV-1 NNRTIs Discovery.

@nl

P1476

Further Exploring Solvent-Expo ...... Novel HIV-1 NNRTIs Discovery.

@en

P2093

Boshi Huang

http://www.w3.org/2001/XMLSchema#string

Da Feng

http://www.w3.org/2001/XMLSchema#string

Dirk Daelemans

http://www.w3.org/2001/XMLSchema#string

Dongwei Kang

http://www.w3.org/2001/XMLSchema#string

Gaochan Wu

http://www.w3.org/2001/XMLSchema#string

Heng Zhang

http://www.w3.org/2001/XMLSchema#string

Jian Zhang

http://www.w3.org/2001/XMLSchema#string

Lanlan Jing

http://www.w3.org/2001/XMLSchema#string

Peng Zhan

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Samuel Guma

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P2860

Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: a review of the last 20 years (1989-2009).

Current status and challenges of antiretroviral research and therapy.

Recent advances in DAPYs and related analogues as HIV-1 NNRTIs.

HIV-1 NNRTIs: structural diversity, pharmacophore similarity, and implications for drug design.

Recent advances in the discovery and development of novel HIV-1 NNRTI platforms (Part II): 2009-2013 update.

Anti-HIV Drug Discovery and Development: Current Innovations and Future Trends.

Design, Synthesis, and Evaluation of Thiophene[3,2-d]pyrimidine Derivatives as HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Significantly Improved Drug Resistance Profiles.

Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approaches.

Novel fused pyrimidine and isoquinoline derivatives as potent HIV-1 NNRTIs: a patent evaluation of WO2016105532A1, WO2016105534A1 and WO2016105564A1.

Structure-Based Optimization of Thiophene[3,2-d]pyrimidine Derivatives as Potent HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Improved Potency against Resistance-Associated Variants.

P304

370-375

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P31

scholarly article

P356

10.1021/ACSMEDCHEMLETT.8B00054

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Erik De Clercq

Christophe Pannecouque

Xinyong Liu

P577

2018-03-01T00:00:00Z

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P698

29670703

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P921

binding pocket

P932

5900328

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