Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome.
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DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down SyndromeForm and Function of Sleep Spindles across the LifespanPotential Role of JAK-STAT Signaling Pathway in the Neurogenic-to-Gliogenic Shift in Down Syndrome BrainTiming of therapies for Down syndrome: the sooner, the betterBuilding an adaptive brain across development: targets for neurorehabilitation must begin in infancyMouse models of Down syndrome as a tool to unravel the causes of mental disabilitiesNeurological phenotypes for Down syndrome across the life spanHippocampal circuit dysfunction in the Tc1 mouse model of Down syndrome.Pharmacotherapy with fluoxetine restores functional connectivity from the dentate gyrus to field CA3 in the Ts65Dn mouse model of down syndromeBrain plasticity and disease: a matter of inhibition.Multiplex genetic fate mapping reveals a novel route of neocortical neurogenesis, which is altered in the Ts65Dn mouse model of Down syndromeGene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development.Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome.Commonality in Down and fetal alcohol syndromes.Role of astroglia in Down's syndrome revealed by patient-derived human-induced pluripotent stem cells.Developmentally altered inhibition in Ts65Dn, a mouse model of Down syndromeS100B and APP promote a gliocentric shift and impaired neurogenesis in Down syndrome neural progenitors.Noninvasive prenatal testing creates an opportunity for antenatal treatment of Down syndrome.Mitotic spindle defects and chromosome mis-segregation induced by LDL/cholesterol-implications for Niemann-Pick C1, Alzheimer's disease, and atherosclerosis.Global DNA hypermethylation in down syndrome placentaDown syndrome--recent progress and future prospects.Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling.Chronic P7C3 treatment restores hippocampal neurogenesis in the Ts65Dn mouse model of Down Syndrome [Corrected].Disruption of neurogenesis and cortical development in transgenic mice misexpressing Olig2, a gene in the Down syndrome critical regionTrisomy 21 and early brain developmentOLIG2 over-expression impairs proliferation of human Down syndrome neural progenitors.miR-155 Is Essential for Inflammation-Induced Hippocampal Neurogenic DysfunctionMolecular and cellular alterations in Down syndrome: toward the identification of targets for therapeuticsFrom abnormal hippocampal synaptic plasticity in down syndrome mouse models to cognitive disability in down syndrome.DYRK1A overexpression enhances STAT activity and astrogliogenesis in a Down syndrome mouse model.Hypocellularity in the Murine Model for Down Syndrome Ts65Dn Is Not Affected by Adult Neurogenesis.Absence of Prenatal Forebrain Defects in the Dp(16)1Yey/+ Mouse Model of Down Syndrome.Activation of p53 in Down Syndrome and in the Ts65Dn Mouse Brain is Associated with a Pro-Apoptotic Phenotype.The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for Down syndromeDyrk1A overexpression inhibits proliferation and induces premature neuronal differentiation of neural progenitor cells.E3 Ligase SCFβTrCP-induced DYRK1A Protein Degradation Is Essential for Cell Cycle Progression in HEK293 Cells.Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21.Poor Sleep as a Precursor to Cognitive Decline in Down Syndrome : A Hypothesis.Nurturing brain plasticity: impact of environmental enrichment.The GABAergic Hypothesis for Cognitive Disabilities in Down Syndrome
P2860
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P2860
Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Neurogenesis impairment and in ...... of fetuses with Down syndrome.
@en
Neurogenesis impairment and in ...... of fetuses with Down syndrome.
@nl
type
label
Neurogenesis impairment and in ...... of fetuses with Down syndrome.
@en
Neurogenesis impairment and in ...... of fetuses with Down syndrome.
@nl
prefLabel
Neurogenesis impairment and in ...... of fetuses with Down syndrome.
@en
Neurogenesis impairment and in ...... of fetuses with Down syndrome.
@nl
P2093
P2860
P50
P1433
P1476
Neurogenesis impairment and in ...... of fetuses with Down syndrome.
@en
P2093
Donatella Santini
Fabio Gualtieri
Paola Bonasoni
Renata Bartesaghi
P2860
P304
P356
10.1111/J.1750-3639.2007.00113.X
P577
2007-12-17T00:00:00Z