The Spy1/RINGO family represents a novel mechanism regulating mammary growth and tumorigenesis.
about
NEDD4: a promising target for cancer therapyEssential role of the Cdk2 activator RingoA in meiotic telomere tethering to the nuclear envelope.The cyclin-like protein, SPY1, regulates the ERα and ERK1/2 pathways promoting tamoxifen resistance.The cyclin-like protein Spy1/RINGO promotes mammary transformation and is elevated in human breast cancerPolymorphic genetic control of tumor invasion in a mouse model of pancreatic neuroendocrine carcinogenesis.Spy1 Protein Mediates Phosphorylation and Degradation of SCG10 Protein in Axonal Degeneration.The atypical CDK activator Spy1 regulates the intrinsic DNA damage response and is dependent upon p53 to inhibit apoptosis.Spy1 participates in the proliferation and apoptosis of epithelial ovarian cancer.Genome-wide analysis of DNA methylation identifies novel cancer-related genes in hepatocellular carcinoma.Spy1 is frequently overexpressed in malignant gliomas and critically regulates the proliferation of glioma cells.The cyclin-dependent kinase activator, Spy1A, is targeted for degradation by the ubiquitin ligase NEDD4.Direct interactions with both p27 and Cdk2 regulate Spy1-mediated proliferation in vivo and in vitro.Structural basis of divergent cyclin-dependent kinase activation by Spy1/RINGO proteins.The atypical cell cycle regulator Spy1 suppresses differentiation of the neuroblastoma stem cell population.Atypical cell cycle control over neural cell fate.Protective roles and Pap1-dependent regulation of the Schizosaccharomyces pombe spy1 gene under nitrosative and nutritional stresses.Temporal-spatial expressions of Spy1 in rat sciatic nerve after crush.CRMP1 Interacted with Spy1 During the Collapse of Growth Cones Induced by Sema3A and Acted on Regeneration After Sciatic Nerve Crush.Expression of Spy1 protein in human non-Hodgkin's lymphomas is correlated with phosphorylation of p27 Kip1 on Thr187 and cell proliferation.
P2860
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P2860
The Spy1/RINGO family represents a novel mechanism regulating mammary growth and tumorigenesis.
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
@wuu
2008年学术文章
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2008年学术文章
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2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
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2008年學術文章
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name
The Spy1/RINGO family represen ...... mary growth and tumorigenesis.
@en
The Spy1/RINGO family represen ...... mary growth and tumorigenesis.
@nl
type
label
The Spy1/RINGO family represen ...... mary growth and tumorigenesis.
@en
The Spy1/RINGO family represen ...... mary growth and tumorigenesis.
@nl
prefLabel
The Spy1/RINGO family represen ...... mary growth and tumorigenesis.
@en
The Spy1/RINGO family represen ...... mary growth and tumorigenesis.
@nl
P2093
P1433
P1476
The Spy1/RINGO family represen ...... mary growth and tumorigenesis.
@en
P2093
Azadeh Golipour
Daniel J Donoghue
Dorothy Myers
Gerard I Evan
Lisa A Porter
Roger A Moorehead
Tiffany Seagroves
P304
P356
10.1158/0008-5472.CAN-07-6453
P407
P577
2008-05-01T00:00:00Z