Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment.
about
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence.NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.The activity of p53 is differentially regulated by Brm- and Brg1-containing SWI/SNF chromatin remodeling complexesA new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosisHLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53Interferon regulatory factor 1 binding to p300 stimulates DNA-dependent acetylation of p53Crosstalk between sumoylation and acetylation regulates p53-dependent chromatin transcription and DNA bindingAcetylation is indispensable for p53 activationTargeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53BAF60a interacts with p53 to recruit the SWI/SNF complexKu86 autoantigen related protein-1 transcription initiates from a CpG island and is induced by p53 through a nearby p53 response elementTranscriptional regulation of the mdm2 oncogene by p53 requires TRRAP acetyltransferase complexesThe C terminus of p53 family proteins is a cell fate determinantVpr-binding protein antagonizes p53-mediated transcription via direct interaction with H3 tailReverse transcriptase-coupled quantitative real time PCR analysis of cell-free transcription on the chromatin-assembled p21 promoterStructural basis for p300 Taz2-p53 TAD1 binding and modulation by phosphorylationA transcription cofactor required for the heat-shock responseRegulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteinsMutant p53 proteins bind DNA in a DNA structure-selective modeCP-31398, a putative p53-stabilizing molecule tested in mammalian cells and in yeast for its effects on p53 transcriptional activityRegulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor.Mechanisms of Hsp90 regulationp53 dynamics upon response element recognition explored by molecular simulations.p53 Transcriptional activity is mediated through the SRC1-interacting domain of CBP/p300CDK8 is a stimulus-specific positive coregulator of p53 target genesThe C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivoThe p53-dependent effects of macrophage migration inhibitory factor revealed by gene targetingChromatin-bound p53 anchors activated Smads and the mSin3A corepressor to confer transforming-growth-factor-beta-mediated transcription repressionModes of p53 regulationMisfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer.Dual promoter structure of mouse and human fatty acid translocase/CD36 genes and unique transcriptional activation by peroxisome proliferator-activated receptor alpha and gamma ligands.The proline repeat domain of p53 binds directly to the transcriptional coactivator p300 and allosterically controls DNA-dependent acetylation of p53.Identification of small-molecule antagonists that inhibit an activator: coactivator interaction.Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with histone deacetylase 1.Noncanonical DNA motifs as transactivation targets by wild type and mutant p53p53 induces distinct epigenetic states at its direct target promoters.Modulation of gene expression in U251 glioblastoma cells by binding of mutant p53 R273H to intronic and intergenic sequencesp53 binding to nucleosomal DNA depends on the rotational positioning of DNA response element.Complex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300.Transcription coactivator CBP has direct DNA binding activity and stimulates transcription factor DNA binding through small domains.
P2860
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P2860
Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Transcriptional regulation by ...... directed cofactor recruitment.
@en
Transcriptional regulation by ...... directed cofactor recruitment.
@nl
type
label
Transcriptional regulation by ...... directed cofactor recruitment.
@en
Transcriptional regulation by ...... directed cofactor recruitment.
@nl
prefLabel
Transcriptional regulation by ...... directed cofactor recruitment.
@en
Transcriptional regulation by ...... directed cofactor recruitment.
@nl
P1433
P1476
Transcriptional regulation by ...... directed cofactor recruitment.
@en
P2093
Emerson BM
Espinosa JM
P356
10.1016/S1097-2765(01)00283-0
P577
2001-07-01T00:00:00Z