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KATNAL1 regulation of sertoli cell microtubule dynamics is essential for spermiogenesis and male fertilityCell-specific ablation in the testis: what have we learned?Androgen receptor roles in spermatogenesis and infertilityProposed role for COUP-TFII in regulating fetal Leydig cell steroidogenesis, perturbation of which leads to masculinization disorders in rodentsAn essential role for katanin p80 and microtubule severing in male gamete productionCandidate testis-determining gene, Maestro (Mro), encodes a novel HEAT repeat proteinHaploinsufficiency of the murine Col3a1 locus causes aortic dissection: a novel model of the vascular type of Ehlers-Danlos syndromeNovel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli CellsLKB1 is an essential regulator of spermatozoa release during spermiation in the mammalian testisSexually dimorphic expression of protease nexin-1 and vanin-1 in the developing mouse gonad prior to overt differentiation suggests a role in mammalian sexual development.The Maestro (Mro) gene is dispensable for normal sexual development and fertility in miceSertoli cells control peritubular myoid cell fate and support adult Leydig cell development in the prepubertal testisIntratubular germ cell neoplasia of the human testis: heterogeneous protein expression and relation to invasive potential.Fetal programming of adult Leydig cell function by androgenic effects on stem/progenitor cellsAndrogen action via testicular peritubular myoid cells is essential for male fertility.Critical androgen-sensitive periods of rat penis and clitoris development.The regulation of spermatogenesis by androgens.Androgen action via testicular arteriole smooth muscle cells is important for Leydig cell function, vasomotion and testicular fluid dynamicsModulation of neointimal lesion formation by endogenous androgens is independent of vascular androgen receptor.Prolonged exposure to acetaminophen reduces testosterone production by the human fetal testis in a xenograft modelSertoli cells maintain Leydig cell number and peritubular myoid cell activity in the adult mouse testisAndrogen receptor signalling in Vascular Endothelial cells is dispensable for spermatogenesis and male fertilityGerm cell-specific targeting of DICER or DGCR8 reveals a novel role for endo-siRNAs in the progression of mammalian spermatogenesis and male fertility.Pituitary androgen receptor signalling regulates prolactin but not gonadotrophins in the male mouse.Deletion of androgen receptor in the smooth muscle of the seminal vesicles impairs secretory function and alters its responsiveness to exogenous testosterone and estradiolExpression of pleiotrophin in the prostate is androgen regulated and it functions as an autocrine regulator of mesenchyme and cancer associated fibroblasts and as a paracrine regulator of epithelia.Diethylstilboestrol exposure does not reduce testosterone production in human fetal testis xenografts.Single primer amplification (SPA) of cDNA for microarray expression analysis.Anogenital distance plasticity in adulthood: implications for its use as a biomarker of fetal androgen actionIdentification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidismDNA microarrays and development.Pleiotropic effects of extended blockade of CSF1R signaling in adult mice.Characterisation of a novel Fc conjugate of macrophage colony-stimulating factor.Deletion of the androgen receptor in adipose tissue in male mice elevates retinol binding protein 4 and reveals independent effects on visceral fat mass and on glucose homeostasis.Targeting of GFP-Cre to the mouse Cyp11a1 locus both drives cre recombinase expression in steroidogenic cells and permits generation of Cyp11a1 knock out mice.Sertoli cell androgen receptor signalling in adulthood is essential for post-meiotic germ cell development.New insights into the role of androgens in wolffian duct stabilization in male and female rodents.Early effects of Sertoli cell-selective androgen receptor ablation on testicular gene expression.Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract.Androgen receptor expression in the caput epididymal epithelium is essential for development of the initial segment and epididymal spermatozoa transit.
P50
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P50
description
researcher
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wetenschapper
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հետազոտող
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name
Lee B Smith
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Lee B Smith
@en
Lee B Smith
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Lee B Smith
@nl
Lee B Smith
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type
label
Lee B Smith
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Lee B Smith
@en
Lee B Smith
@es
Lee B Smith
@nl
Lee B Smith
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prefLabel
Lee B Smith
@ast
Lee B Smith
@en
Lee B Smith
@es
Lee B Smith
@nl
Lee B Smith
@sl
P106
P31
P496
0000-0002-4103-3074