IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma.

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PPP2R1A regulated by PAX3/FOXO1 fusion contributes to the acquisition of aggressive behavior in PAX3/FOXO1-positive alveolar rhabdomyosarcoma.

P2860

Q54977242-AA45D7AA-2F15-46F8-B342-20B4C6AF20D4

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IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma.

Item

http://www.wikidata.org/entity/Q52629172

description

2018 nî lūn-bûn

@nan

2018年の論文

@ja

2018年学术文章

@wuu

2018年学术文章

@zh

2018年学术文章

@zh-cn

2018年学术文章

@zh-hans

2018年学术文章

@zh-my

2018年学术文章

@zh-sg

2018年學術文章

@yue

2018年學術文章

@zh-hant

name

IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma.

@en

IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma.

@nl

type

Item

label

IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma.

@en

IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma.

@nl

prefLabel

IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma.

@en

IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma.

@nl

P1476

IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma.

@en

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Kazuo Kaneko

http://www.w3.org/2001/XMLSchema#string

Keisuke Akaike

http://www.w3.org/2001/XMLSchema#string

Kenta Mukaihara

http://www.w3.org/2001/XMLSchema#string

Midori Ishii

http://www.w3.org/2001/XMLSchema#string

Saiko Kazuno

http://www.w3.org/2001/XMLSchema#string

Shinji Kohsaka

http://www.w3.org/2001/XMLSchema#string

Taisei Kurihara

http://www.w3.org/2001/XMLSchema#string

Taketo Okubo

http://www.w3.org/2001/XMLSchema#string

Takuo Hayashi

http://www.w3.org/2001/XMLSchema#string

Tsuyoshi Saito

http://www.w3.org/2001/XMLSchema#string

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Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

Unconventional splicing of XBP1 mRNA occurs in the cytoplasm during the mammalian unfolded protein response

Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma

Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma

Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing

Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

The mammalian unfolded protein response

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

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14428-14443

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scholarly article

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10.18632/ONCOTARGET.24467

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English

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http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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2018-02-12T00:00:00Z

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P698

29581854

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P932

5865680

http://www.w3.org/2001/XMLSchema#string

IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma.

about

P2860

P2860

IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma.

description

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type

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prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P698

P932