Mapping the Allosteric Action of Antagonists A740003 and A438079 Reveals a Role for the Left Flipper in Ligand Sensitivity at P2X7 Receptors.

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Mapping the Allosteric Action of Antagonists A740003 and A438079 Reveals a Role for the Left Flipper in Ligand Sensitivity at P2X7 Receptors.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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Mapping the Allosteric Action ...... Sensitivity at P2X7 Receptors.

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Mapping the Allosteric Action ...... Sensitivity at P2X7 Receptors.

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Mapping the Allosteric Action ...... Sensitivity at P2X7 Receptors.

@en

Mapping the Allosteric Action ...... Sensitivity at P2X7 Receptors.

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Mapping the Allosteric Action ...... Sensitivity at P2X7 Receptors.

@en

Mapping the Allosteric Action ...... Sensitivity at P2X7 Receptors.

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P1476

Mapping the Allosteric Action ...... Sensitivity at P2X7 Receptors.

@en

P2093

Anfal Bin Dayel

http://www.w3.org/2001/XMLSchema#string

Rebecca C Allsopp

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Richard J Evans

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Sudad Dayl

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P2860

Molecular and functional properties of P2X receptors--recent progress and persisting challenges

Exploring the ATP-binding site of P2X receptors

The P2X7 receptor channel: recent developments and the use of P2X7 antagonists in models of disease

Principles and properties of ion flow in P2X receptors

Molecular physiology of P2X receptors

A-740003 [N-(1-{[(cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a novel and selective P2X7 receptor antagonist, dose-dependently reduces neuropathic pain in the rat

Unique residues in the ATP gated human P2X7 receptor define a novel allosteric binding pocket for the selective antagonist AZ10606120.

Mutation of putative N-linked glycosylation sites on the human nucleotide receptor P2X7 reveals a key residue important for receptor function.

Structure-activity relationship studies on a series of novel, substituted 1-benzyl-5-phenyltetrazole P2X7 antagonists.

P2X7 receptor inhibition protects against ischemic acute kidney injury in mice.

P304

553-562

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scholarly article

P356

10.1124/MOL.117.111021

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P433

http://www.w3.org/2001/XMLSchema#string

P478

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P50

Ralf Schmid

P577

2018-03-13T00:00:00Z

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P698

29535152

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P932

5896373

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