Paradoxical roles of ATF6α and ATF6β in modulating disease severity caused by mutations in collagen X.

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A lifetime of stress: ATF6 in development and homeostasis.

P2860

Q54978196-04AEEAE1-AD2D-4CBB-9C7B-5D7E8BF0A388

P2860

Paradoxical roles of ATF6α and ATF6β in modulating disease severity caused by mutations in collagen X.

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http://www.wikidata.org/entity/Q52664254

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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Paradoxical roles of ATF6α and ...... ed by mutations in collagen X.

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Paradoxical roles of ATF6α and ...... ed by mutations in collagen X.

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type

Item

label

Paradoxical roles of ATF6α and ...... ed by mutations in collagen X.

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Paradoxical roles of ATF6α and ...... ed by mutations in collagen X.

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Paradoxical roles of ATF6α and ...... sed by mutations in collagen X

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Paradoxical roles of ATF6α and ...... ed by mutations in collagen X.

@en

Paradoxical roles of ATF6α and ...... ed by mutations in collagen X.

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P1476

Paradoxical roles of ATF6α and ...... sed by mutations in collagen X

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P2093

K Mori

http://www.w3.org/2001/XMLSchema#string

M Forouhan

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P2860

Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells

Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response

Mechanisms and models of endoplasmic reticulum stress in chondrodysplasia

Regulated translation initiation controls stress-induced gene expression in mammalian cells

ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

P304

50-71

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scholarly article

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10.1016/J.MATBIO.2018.03.004

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English

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Raymond P Boot-Handford

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2018-03-06T00:00:00Z

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29522813

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molecular biology

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6090092

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Paradoxical roles of ATF6α and ATF6β in modulating disease severity caused by mutations in collagen X.

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P2860

P2860

Paradoxical roles of ATF6α and ATF6β in modulating disease severity caused by mutations in collagen X.

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type

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P478

P50

P577

P698

P921

P932