Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.
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Oximes: inhibitors of human recombinant acetylcholinesterase. A structure-activity relationship (SAR) studyDesign, evaluation and structure-activity relationship studies of the AChE reactivators against organophosphorus pesticides.In Vitro Comparison of Two Most Promising H-Oximes (HI-6 and HLö-7) and Currently Commercially Available Reactivators Pralidoxime and Obidoxime in Reactivation of Cyclosarin-Inhibited Human Cholinesterases.The present approaches to the development of prophylactic and therapeutic antidotes against nerve agents.In vitro reactivation kinetics of paraoxon- and DFP-inhibited electric eel AChE using mono- and bis-pyridinium oximes.New series of monoquaternary pyridinium oximes: Synthesis and reactivation potency for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase.New K-Oximes (K-27 and K-48) in Comparison with Obidoxime (LuH-6), HI-6, Trimedoxime (TMB-4), and Pralidoxime (2-PAM): Survival in Rats Exposed IP to the Organophosphate Paraoxon.Efficacy of two new asymmetric bispyridinium oximes (K-27 and K-48) in rats exposed to diisopropylfluorophosphate: comparison with pralidoxime, obidoxime, trimedoxime, methoxime, and HI-6.In vitro oxime-assisted reactivation of paraoxon-inhibited human acetylcholinesterase and butyrylcholinesterase.Targeted synthesis of 1-(4-hydroxyiminomethylpyridinium)-3-pyridiniumpropane dibromide--a new nerve agent reactivator.Novel Group of AChE Reactivators-Synthesis, In Vitro Reactivation and Molecular Docking Study
P2860
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P2860
Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Synthesis of asymmetrical bisp ...... nhibited acetylcholinesterase.
@en
Synthesis of asymmetrical bisp ...... nhibited acetylcholinesterase.
@nl
type
label
Synthesis of asymmetrical bisp ...... nhibited acetylcholinesterase.
@en
Synthesis of asymmetrical bisp ...... nhibited acetylcholinesterase.
@nl
prefLabel
Synthesis of asymmetrical bisp ...... nhibited acetylcholinesterase.
@en
Synthesis of asymmetrical bisp ...... nhibited acetylcholinesterase.
@nl
P50
P1476
Synthesis of asymmetrical bisp ...... inhibited acetylcholinesterase
@en
P2093
Kamil Kuca
P304
P356
10.1016/J.BMCL.2006.08.011
P407
P577
2006-08-24T00:00:00Z