Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker: preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase.

Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker: preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase.

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http://www.wikidata.org/entity/Q52683047
Design, evaluation and structure-activity relationship studies of the AChE reactivators against organophosphorus pesticides.Toxicological considerations of acetylcholinesterase reactivators.Mini review on blood-brain barrier penetration of pyridinium aldoximes.The present approaches to the development of prophylactic and therapeutic antidotes against nerve agents.Bisquaternary pyridinium oximes: Comparison of in vitro reactivation potency of compounds bearing aliphatic linkers and heteroaromatic linkers for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase.Effect of seven newly synthesized and currently available oxime cholinesterase reactivators on cyclosarin-intoxicated rats.Effect of several new and currently available oxime cholinesterase reactivators on tabun-intoxicated rats.A comparison of the reactivating and therapeutic efficacy of newly developed bispyridinium oximes (K250, K251) with commonly used oximes against tabun in rats and mice.An evaluation of reactivating and therapeutic efficacy of newly developed oximes (K206, K269) and commonly used oximes (obidoxime, HI-6) in cyclosarin-poisoned rats and mice.Oxime-mediated in vitro reactivation kinetic analysis of organophosphates-inhibited human and electric eel acetylcholinesterase.Changes of rat plasma total low molecular weight antioxidant level after tabun exposure and consequent treatment by acetylcholinesterase reactivators.Reactivation kinetics of a homologous series of bispyridinium bis-oximes with nerve agent-inhibited human acetylcholinesterase.Revealing the importance of linkers in K-series oxime reactivators for tabun-inhibited AChE using quantum chemical, docking and SMD studies.The benefit of combinations of oximes for the ability of antidotal treatment to counteract sarin-induced brain damage in rats.Novel Group of AChE Reactivators-Synthesis, In Vitro Reactivation and Molecular Docking Study
P2860

Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker: preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase.

Item
http://www.wikidata.org/entity/Q52683047
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Monooxime reactivators of acet ...... nhibited acetylcholinesterase.
@en
Monooxime reactivators of acetylcholinesterase with
@nl
type
label
Monooxime reactivators of acet ...... nhibited acetylcholinesterase.
@en
Monooxime reactivators of acetylcholinesterase with
@nl
prefLabel
Monooxime reactivators of acet ...... nhibited acetylcholinesterase.
@en
Monooxime reactivators of acetylcholinesterase with
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Monooxime reactivators of acet ...... inhibited acetylcholinesterase
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698