Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency.

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A Disturbance in the Force: Cellular Stress Sensing by the Mitochondrial Network

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Q58702057-476E2128-A890-47A2-ACE5-1999C717B19A

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Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency.

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2018 nî lūn-bûn

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Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency.

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Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency.

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Item

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Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency.

@en

Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency.

@nl

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Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency.

@en

Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency.

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P1476

Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency

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Aida Rodríguez-Nuevo

http://www.w3.org/2001/XMLSchema#string

Angels Díaz-Ramos

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Caterina Tezze

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David Sebastián

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Eduard Noguera

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Evarist Planet

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Francesc Ribas

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Francisco Díaz-Sáez

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Javier González

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Joan Vendrell

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P2860

Mitochondrial DNA stress primes the antiviral innate immune response

OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

OPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypes

Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers

Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in mice

OPA1 requires mitofusin 1 to promote mitochondrial fusion

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control

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scholarly article

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10.15252/EMBJ.201796553

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English

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http://www.w3.org/2001/XMLSchema#string

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http://www.w3.org/2001/XMLSchema#string

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P577

2018-04-09T00:00:00Z

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29632021

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mitochondrial DNA

Toll-like receptor

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5978453

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Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency.

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P2860

P2860

Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932