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Beyond model antigens: high-dimensional methods for the analysis of antigen-specific T cellsCategorical Analysis of Human T Cell Heterogeneity with One-Dimensional Soli-Expression by Nonlinear Stochastic Embedding.Structures of neuroligin-1 and the neuroligin-1/neurexin-1 beta complex reveal specific protein-protein and protein-Ca2+ interactionsStructural Basis of Specificity and Cross-Reactivity in T Cell Receptors Specific for Cytochrome c-I-ERegulation of a TRPM7-like current in rat brain microgliaEvidence for a functional sidedness to the alphabetaTCR.Photocrosslinkable pMHC monomers stain T cells specifically and cause ligand-bound TCRs to be 'preferentially' transported to the cSMAC.Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypesCombinatorial tetramer staining and mass cytometry analysis facilitate T-cell epitope mapping and characterization.OpenCyto: an open source infrastructure for scalable, robust, reproducible, and automated, end-to-end flow cytometry data analysisCytofkit: A Bioconductor Package for an Integrated Mass Cytometry Data Analysis PipelineDeep Sequencing in Infectious Diseases: Immune and Pathogen Repertoires for the Improvement of Patient OutcomesHost sirtuin 1 regulates mycobacterial immunopathogenesis and represents a therapeutic target against tuberculosis.Gamma delta T cells recognize haptens and mount a hapten-specific response.CD161 defines a transcriptional and functional phenotype across distinct human T cell lineages.Characterization of influenza vaccine immunogenicity using influenza antigen microarrays.Regulation of hERG and hEAG channels by Src and by SHP-1 tyrosine phosphatase via an ITIM region in the cyclic nucleotide binding domainTetramers reveal IL-17-secreting CD4+ T cells that are specific for U1-70 in lupus and mixed connective tissue disease.Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8(+) T Lymphocytes.TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity.Mass cytometry: blessed with the curse of dimensionality.Novel therapeutic targets on the horizon for lung cancer.Adenoviral Vector Vaccination Induces a Conserved Program of CD8(+) T Cell Memory Differentiation in Mouse and Man.γδ T cells recognize a microbial encoded B cell antigen to initiate a rapid antigen-specific interleukin-17 response.Multiparameter Phenotyping of Human PBMCs Using Mass Cytometry.mir-181a-1/b-1 Modulates Tolerance through Opposing Activities in Selection and Peripheral T Cell FunctionInterrogating the repertoire: broadening the scope of peptide-MHC multimer analysisThe promised land of human immunologyDietary gluten triggers concomitant activation of CD4+ and CD8+ αβ T cells and γδ T cells in celiac diseaseUnsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species.Simultaneous detection of many T-cell specificities using combinatorial tetramer staining.High-dimensional analysis of human CD8(+) T cell phenotype, function, and antigen specificity.Higher throughput methods of identifying T cell epitopes for studying outcomes of altered antigen processing and presentationInduced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function.Immune Checkpoint Function of CD85j in CD8 T Cell Differentiation and Aging.Intrahepatic CD206+ macrophages contribute to inflammation in advanced viral-related liver disease.Deep Profiling Human T Cell Heterogeneity by Mass Cytometry.High-dimensional immune profiling of total and rotavirus VP6-specific intestinal and circulating B cells by mass cytometry.CD161(int)CD8+ T cells: a novel population of highly functional, memory CD8+ T cells enriched within the gut.T-Cell Receptor (TCR) Clonotype-Specific Differences in Inhibitory Activity of HIV-1 Cytotoxic T-Cell Clones Is Not Mediated by TCR Alone.
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Evan W Newell
@ast
Evan W Newell
@en
Evan W Newell
@es
Evan W Newell
@nl
Evan W Newell
@sl
type
label
Evan W Newell
@ast
Evan W Newell
@en
Evan W Newell
@es
Evan W Newell
@nl
Evan W Newell
@sl
prefLabel
Evan W Newell
@ast
Evan W Newell
@en
Evan W Newell
@es
Evan W Newell
@nl
Evan W Newell
@sl
P108
P1053
F-9711-2012
P106
P108
P31
P3829
P3835
evan-newell
P496
0000-0002-2889-243X