Preferential mutation of paternally derived RB gene as the initial event in sporadic osteosarcoma.
about
The regions of the retinoblastoma protein needed for binding to adenovirus E1A or SV40 large T antigen are common sites for mutationsThe retinoblastoma protein is phosphorylated on multiple sites by human cdc2Parent-of-origin effects in multiple endocrine neoplasia type 2BReview of Osteosarcoma and Current ManagementPreferential amplification of the paternal allele of the N-myc gene in human neuroblastomasA model for embryonal rhabdomyosarcoma tumorigenesis that involves genome imprinting.Tumor-suppressor genes: cardinal factors in inherited predisposition to human cancersEqual parental origin of chromosome 22 losses in human sporadic meningioma: no evidence for genomic imprinting.Genomic imprinting: review and relevance to human diseases.The human retinoblastoma gene is imprinted.Genomic imprinting: implications for human disease.Parental bias of Ki-ras oncogenes detected in lung tumors from mouse hybrids.Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteTumour suppressor gene mutations in humans and mice: parallels and contrastsThe clonal origin and clonal evolution of epithelial tumours.Germline selection: population genetic aspects of the sexual/asexual life cycle.Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region.Genomic imprintingMalignancy: Tumor Suppressor Gene Aberrations in Acute Myelogenous Leukemia.Genomic imprinting proposed as a surveillance mechanism for chromosome loss.Constitutional 1p36 deletion in a child with neuroblastoma.Genomic imprinting: mechanism and role in human pathology.Genomic imprinting of the human serotonin-receptor (HTR2) gene involved in development of retinoblastoma.Concordance between parental origin of chromosome 13q loss and chromosome 6p duplication in sporadic retinoblastomaHigh-throughput detection of aberrant imprint methylation in the ovarian cancer by the bisulphite PCR-Luminex methodTumor suppressor genetics.Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcomaMouse models of sarcomas: critical tools in our understanding of the pathobiologyBiological characterization of soft tissue sarcomasVery high incidence of germ cell tumorigenesis (seminomagenesis) in human papillomavirus type 16 transgenic miceAntibodies specific for the human retinoblastoma protein identify a family of related polypeptides.The retinoblastoma protein physically associates with the human cdc2 kinase.Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice.Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene productp27 Is a Candidate Prognostic Biomarker and Metastatic Promoter in Osteosarcoma.Tumor suppressor genes and cancer of the human nervous system.Immune response to RB1-regulated senescence limits radiation-induced osteosarcoma formation.Cause and consequences of genetic and epigenetic alterations in human cancer.Molecular mechanisms of genomic imprinting and clinical implications for cancer.More epigenetic hits than meets the eye: microRNAs and genes associated with the tumorigenesis of retinoblastoma.
P2860
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P2860
Preferential mutation of paternally derived RB gene as the initial event in sporadic osteosarcoma.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh-hant
name
Preferential mutation of pater ...... vent in sporadic osteosarcoma.
@en
Preferential mutation of pater ...... vent in sporadic osteosarcoma.
@nl
type
label
Preferential mutation of pater ...... vent in sporadic osteosarcoma.
@en
Preferential mutation of pater ...... vent in sporadic osteosarcoma.
@nl
prefLabel
Preferential mutation of pater ...... vent in sporadic osteosarcoma.
@en
Preferential mutation of pater ...... vent in sporadic osteosarcoma.
@nl
P2093
P2860
P356
P1433
P1476
Preferential mutation of pater ...... vent in sporadic osteosarcoma.
@en
P2093
Ishizaki K
Nakamura Y
Toguchida J
Yamamuro T
P2860
P2888
P304
P356
10.1038/338156A0
P407
P577
1989-03-01T00:00:00Z
P6179
1036766238