MAPK8-mediated stabilization of SP1 is essential for RUNX1-RUNX1T1 - driven leukaemia.

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MAPK8-mediated stabilization of SP1 is essential for RUNX1-RUNX1T1 - driven leukaemia.

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

@zh

2015年学术文章

@zh-cn

2015年学术文章

@zh-hans

2015年学术文章

@zh-my

2015年学术文章

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2015年學術文章

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2015年學術文章

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MAPK8-mediated stabilization of SP1 is essential for RUNX1-RUNX1T1 - driven leukaemia.

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MAPK8-mediated stabilization of SP1 is essential for RUNX1-RUNX1T1 - driven leukaemia.

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MAPK8-mediated stabilization of SP1 is essential for RUNX1-RUNX1T1 - driven leukaemia.

@en

MAPK8-mediated stabilization of SP1 is essential for RUNX1-RUNX1T1 - driven leukaemia.

@nl

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MAPK8-mediated stabilization of SP1 is essential for RUNX1-RUNX1T1 - driven leukaemia.

@en

MAPK8-mediated stabilization of SP1 is essential for RUNX1-RUNX1T1 - driven leukaemia.

@nl

P1476

MAPK8-mediated stabilization of SP1 is essential for RUNX1-RUNX1T1 - driven leukaemia

@en

P2093

Amanda Sánchez-López

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Ana Rio-Machin

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James C Mulloy

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Juan C Cigudosa

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Mahesh Shrestha

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Sara Alvarez

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P2860

Activation of the p21WAF1/CIP1 promoter independent of p53 by the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through the Sp1 sites.

Sp1/NFkappaB/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemia.

p53 signaling in response to increased DNA damage sensitizes AML1-ETO cells to stress-induced death

Bortezomib induces DNA hypomethylation and silenced gene transcription by interfering with Sp1/NF-kappaB-dependent DNA methyltransferase activity in acute myeloid leukemia.

Phosphorylation by c-Jun NH2-terminal kinase 1 regulates the stability of transcription factor Sp1 during mitosis

Transcriptional upregulation of p21/WAF/Cip1 in myeloid leukemic blasts expressing AML1-ETO.

Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein.

The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells.

Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells.

Chromatin modifications induced by the AML1-ETO fusion protein reversibly silence its genomic targets through AML1 and Sp1 binding motifs.

P304

807-810

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P31

scholarly article

P356

10.1111/BJH.13536

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P407

English

P433

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P478

172

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P50

Miriam Hernando-Rodríguez

Alba Maiques

P577

2015-06-08T00:00:00Z

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P5875

278045352

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P698

26058961

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P921

leukemia