TRIM24 promotes glioma progression and enhances chemoresistance through activation of the PI3K/Akt signaling pathway.
about
The polar warhead of a TRIM24 bromodomain inhibitor rearranges a water-mediated interaction network.TRIM24 promotes the aggression of gastric cancer via the Wnt/β-catenin signaling pathway.Transcriptional profiling provides insights into metronomic cyclophosphamide-activated, innate immune-dependent regression of brain tumor xenograftsCDK4 and miR-15a comprise an abnormal automodulatory feedback loop stimulating the pathogenesis and inducing chemotherapy resistance in nasopharyngeal carcinoma.Clinical significance and prognostic value of TRIM24 expression in esophageal squamous cell carcinoma.Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.TRIM24 suppresses development of spontaneous hepatic lipid accumulation and hepatocellular carcinoma in mice.TRIM24 Is an Oncogenic Transcriptional Activator in Prostate Cancer.Glucose transporter 4 promotes head and neck squamous cell carcinoma metastasis through the TRIM24-DDX58 axis.Downregulation of ARHGDIA contributes to human glioma progression through activation of Rho GTPase signaling pathway.Regulation of TRIM24 by miR-511 modulates cell proliferation in gastric cancer.Overexpression of TRIM24 is correlated with the progression of human cervical cancer.Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.Histone H3 lysine 23 acetylation is associated with oncogene TRIM24 expression and a poor prognosis in breast cancer.Expanding the Circuitry of Pluripotency by Selective Isolation of Chromatin-Associated Proteins.TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma.Histone Acetyltransferase KAT6A Upregulates PI3K/AKT Signaling through TRIM24 Binding.The dual PI3K/mTOR inhibitor dactolisib elicits anti-tumor activity in vitro and in vivo.TRIM24 is upregulated in human gastric cancer and promotes gastric cancer cell growth and chemoresistance.
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P2860
TRIM24 promotes glioma progression and enhances chemoresistance through activation of the PI3K/Akt signaling pathway.
description
2014 nî lūn-bûn
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name
TRIM24 promotes glioma progres ...... he PI3K/Akt signaling pathway.
@en
TRIM24 promotes glioma progres ...... he PI3K/Akt signaling pathway.
@nl
type
label
TRIM24 promotes glioma progres ...... he PI3K/Akt signaling pathway.
@en
TRIM24 promotes glioma progres ...... he PI3K/Akt signaling pathway.
@nl
prefLabel
TRIM24 promotes glioma progres ...... he PI3K/Akt signaling pathway.
@en
TRIM24 promotes glioma progres ...... he PI3K/Akt signaling pathway.
@nl
P2093
P2860
P356
P1433
P1476
TRIM24 promotes glioma progres ...... he PI3K/Akt signaling pathway.
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2013.593
P407
P50
P577
2014-01-27T00:00:00Z