Non-invasive quantification of the beta cell mass by SPECT with ¹¹¹In-labelled exendin.
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Evaluation of ¹¹¹in-labelled exendin-4 derivatives containing different meprin β-specific cleavable linkersA 3D map of the islet routes throughout the healthy human pancreas.Automated assessment of β-cell area and density per islet and patient using TMEM27 and BACE2 immunofluorescence staining in human pancreatic β-cells.Targeting GLP-1 receptors for repeated magnetic resonance imaging differentiates graded losses of pancreatic beta cells in mice.Combined Optical Coherence and Fluorescence Microscopy to assess dynamics and specificity of pancreatic beta-cell tracers.Graft revascularization is essential for non-invasive monitoring of transplanted islets with radiolabeled exendinA Synthetic Heterobivalent Ligand Composed of Glucagon-Like Peptide 1 and Yohimbine Specifically Targets β Cells Within the PancreasCross-sectional and Test-Retest Characterization of PET with [(18)F]FP-(+)-DTBZ for β Cell Mass Estimates in Diabetes.SPECT-OPT multimodal imaging enables accurate evaluation of radiotracers for β-cell mass assessments.(111)In-exendin uptake in the pancreas correlates with the β-cell mass and not with the α-cell massStrategies for clinical trials in type 1 diabetesDeletion of β-Arrestin2 in mice limited pancreatic beta-cell expansion under metabolic stress through activation of JNK pathway.Strain Differences Determine the Suitability of Animal Models for Noninvasive In Vivo Beta Cell Mass Determination with Radiolabeled ExendinA 3D-printed anatomical pancreas and kidney phantom for optimizing SPECT/CT reconstruction settings in beta cell imaging using 111In-exendin.Whole organ and islet of Langerhans dosimetry for calculation of absorbed doses resulting from imaging with radiolabeled exendinTargets and probes for non-invasive imaging of β-cells.Pancreatic β-cell imaging in humans: fiction or option?In vivo imaging of beta cells with radiotracers: state of the art, prospects and recommendations for development and use.GPR44 is a pancreatic protein restricted to the human beta cell.A standardized method for in vivo mouse pancreas imaging and semiquantitative β cell mass measurement by dual isotope SPECT.Fully automated GMP production of [68Ga]Ga-DO3A-VS-Cys40-Exendin-4 for clinical use.Non-invasive in vivo determination of viable islet graft volume by 111In-exendin-3.Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis.Low kidney uptake of GLP-1R-targeting, beta cell-specific PET tracer, 18F-labeled [Nle14,Lys40]exendin-4 analog, shows promise for clinical imaging.Radiomanganese PET Detects Changes in Functional β-Cell Mass in Mouse Models of Diabetes.Multiorgan, Multimodality Imaging in Cardiometabolic Disease.Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer
P2860
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P2860
Non-invasive quantification of the beta cell mass by SPECT with ¹¹¹In-labelled exendin.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
@wuu
2014年学术文章
@zh
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
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2014年學術文章
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2014年學術文章
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name
Non-invasive quantification of the beta cell mass by SPECT with ¹¹¹In-labelled exendin.
@en
Non-invasive quantification of the beta cell mass by SPECT with ¹¹¹In-labelled exendin.
@nl
type
label
Non-invasive quantification of the beta cell mass by SPECT with ¹¹¹In-labelled exendin.
@en
Non-invasive quantification of the beta cell mass by SPECT with ¹¹¹In-labelled exendin.
@nl
prefLabel
Non-invasive quantification of the beta cell mass by SPECT with ¹¹¹In-labelled exendin.
@en
Non-invasive quantification of the beta cell mass by SPECT with ¹¹¹In-labelled exendin.
@nl
P2093
P2860
P50
P1433
P1476
Non-invasive quantification of the beta cell mass by SPECT with ¹¹¹In-labelled exendin.
@en
P2093
Burkhard J Göke
Cathelijne Frielink
Cees J Tack
Decio L Eizirik
Karolina Andralojc
Lieke Joosten
Marcel Janssen
Marion de Jong
Martin Béhé
Martin Gotthardt
P2860
P2888
P304
P356
10.1007/S00125-014-3166-3
P577
2014-02-01T00:00:00Z