Optimisation of BACE1 inhibition of tripartite structures by modification of membrane anchors, spacers and pharmacophores - development of potential agents for the treatment of Alzheimer's disease.
about
Presumed LRP1-targeting transport peptide delivers β-secretase inhibitor to neurons in vitro with limited efficiencySolid-Phase Synthesis and Characterization of N-Terminally Elongated Aβ-3-x -Peptides.Insights into the Impact of a Membrane-Anchoring Moiety on the Biological Activities of Bivalent Compounds As Potential Neuroprotectants for Alzheimer's Disease.Design and characterization of bivalent compounds as potential neuroprotectants for Alzheimer's disease: Impact of the spacer on biological activity.
P2860
Optimisation of BACE1 inhibition of tripartite structures by modification of membrane anchors, spacers and pharmacophores - development of potential agents for the treatment of Alzheimer's disease.
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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2012年學術文章
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name
Optimisation of BACE1 inhibiti ...... atment of Alzheimer's disease.
@en
Optimisation of BACE1 inhibiti ...... atment of Alzheimer's disease.
@nl
type
label
Optimisation of BACE1 inhibiti ...... atment of Alzheimer's disease.
@en
Optimisation of BACE1 inhibiti ...... atment of Alzheimer's disease.
@nl
prefLabel
Optimisation of BACE1 inhibiti ...... atment of Alzheimer's disease.
@en
Optimisation of BACE1 inhibiti ...... atment of Alzheimer's disease.
@nl
P2093
P2860
P356
P1476
Optimisation of BACE1 inhibiti ...... atment of Alzheimer's disease.
@en
P2093
Hans-Joachim Knölker
Hans-Wolfgang Klafki
Heinke Schieb
Isaak Beyer
Philipp Linning
Sebastian Weidlich
Ute Haussmann
P2860
P304
P356
10.1039/C2OB26103K
P577
2012-10-01T00:00:00Z