Supramolecular structural constraints on Alzheimer's beta-amyloid fibrils from electron microscopy and solid-state nuclear magnetic resonance.
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Structural conversion of neurotoxic amyloid-beta(1-42) oligomers to fibrilsElectrochemistry of nonconjugated proteins and glycoproteins. Toward sensors for biomedicine and glycomicsMolecular structural basis for polymorphism in Alzheimer's -amyloid fibrilsAntiparallel -sheet architecture in Iowa-mutant -amyloid fibrilsAtomic Resolution Structure of Monomorphic Aβ42 Amyloid FibrilsMolecular Structure of Aggregated Amyloid-β: Insights from Solid-State Nuclear Magnetic ResonanceNeuroserpin binds Abeta and is a neuroprotective component of amyloid plaques in Alzheimer diseaseSite-specific identification of non-beta-strand conformations in Alzheimer's beta-amyloid fibrils by solid-state NMRA structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMRExperimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrilsSolid-state NMR as a probe of amyloid structureCharacterization of amyloid structures at the molecular level by solid state nuclear magnetic resonance spectroscopyStructural Polymorphism of Alzheimer's β-Amyloid Fibrils as Controlled by an E22 Switch: A Solid-State NMR StudyIntermolecular structure determination of amyloid fibrils with magic-angle spinning and dynamic nuclear polarization NMR.High-resolution MAS NMR analysis of PI3-SH3 amyloid fibrils: backbone conformation and implications for protofilament assembly and structure .Atomic-resolution structure of a disease-relevant Aβ(1-42) amyloid fibril.Structural differences between Abeta(1-40) intermediate oligomers and fibrils elucidated by proteolytic fragmentation and hydrogen/deuterium exchange.Simultaneous monitoring of peptide aggregate distributions, structure, and kinetics using amide hydrogen exchange: application to Abeta(1-40) fibrillogenesisInterprotofilament interactions between Alzheimer's Abeta1-42 peptides in amyloid fibrils revealed by cryoEMAggregation and fibril morphology of the Arctic mutation of Alzheimer's Aβ peptide by CD, TEM, STEM and in situ AFMA new structural model of Alzheimer's Aβ42 fibrils based on electron paramagnetic resonance data and Rosetta modelingFlexibility and Solvation of Amyloid-β Hydrophobic CoreParallel beta-sheets and polar zippers in amyloid fibrils formed by residues 10-39 of the yeast prion protein Ure2p.Measurement of amyloid fibril mass-per-length by tilted-beam transmission electron microscopy.Molecular structures of quiescently grown and brain-derived polymorphic fibrils of the Alzheimer amyloid abeta9-40 peptide: a comparison to agitated fibrils.The turn formation at positions 22 and 23 in the 42-mer amyloid beta peptide: the emerging role in the pathogenesis of Alzheimer's disease.Fibrillar oligomers nucleate the oligomerization of monomeric amyloid beta but do not seed fibril formationAmyloid structure and assembly: insights from scanning transmission electron microscopy.Intrinsic linear heterogeneity of amyloid β protein fibrils revealed by higher resolution mass-per-length determinations.[PSI+] maintenance is dependent on the composition, not primary sequence, of the oligopeptide repeat domain.Polymorphism in Alzheimer Abeta amyloid organization reflects conformational selection in a rugged energy landscape.Amyloid structure: conformational diversity and consequences.Fibril structure of human islet amyloid polypeptide.The α-helical C-terminal domain of full-length recombinant PrP converts to an in-register parallel β-sheet structure in PrP fibrils: evidence from solid state nuclear magnetic resonance.Physical and structural basis for polymorphism in amyloid fibrilsStructural evolution of Iowa mutant β-amyloid fibrils from polymorphic to homogeneous states under repeated seeded growthSystematic examination of polymorphism in amyloid fibrils by molecular-dynamics simulation.Solid-state NMR studies of amyloid fibril structureThe crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy.Molecular alignment within beta-sheets in Abeta(14-23) fibrils: solid-state NMR experiments and theoretical predictions.
P2860
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P2860
Supramolecular structural constraints on Alzheimer's beta-amyloid fibrils from electron microscopy and solid-state nuclear magnetic resonance.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Supramolecular structural cons ...... te nuclear magnetic resonance.
@en
Supramolecular structural cons ...... te nuclear magnetic resonance.
@nl
type
label
Supramolecular structural cons ...... te nuclear magnetic resonance.
@en
Supramolecular structural cons ...... te nuclear magnetic resonance.
@nl
prefLabel
Supramolecular structural cons ...... te nuclear magnetic resonance.
@en
Supramolecular structural cons ...... te nuclear magnetic resonance.
@nl
P2093
P356
P1433
P1476
Supramolecular structural cons ...... te nuclear magnetic resonance.
@en
P2093
John J Balbach
Oleg N Antzutkin
Richard D Leapman
P304
15436-15450
P356
10.1021/BI0204185
P407
P50
P577
2002-12-01T00:00:00Z