Chemoprevention of UV light-induced skin tumorigenesis by inhibition of the epidermal growth factor receptor.
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Arsenite and insulin exhibit opposing effects on epidermal growth factor receptor and keratinocyte proliferative potentialMetabolic signature of sun exposed skin suggests catabolic pathway overweighs anabolic pathwayEpidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signalingDual inhibition of both the epidermal growth factor receptor and erbB2 effectively inhibits the promotion of skin tumors during two-stage carcinogenesis.The prostaglandin E2 receptor, EP2, stimulates keratinocyte proliferation in mouse skin by G protein-dependent and {beta}-arrestin1-dependent signaling pathways.Low-dose UVB irradiation stimulates matrix metalloproteinase-1 expression via a BLT2-linked pathway in HaCaT cellsAnti-photoaging effects of soy isoflavone extract (aglycone and acetylglucoside form) from soybean cake.Erbb2 regulates inflammation and proliferation in the skin after ultraviolet irradiationEGFR activation and ultraviolet light-induced skin carcinogenesis.Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation.Activation of Peroxisome Proliferator-Activated Receptor Alpha Improves Aged and UV-Irradiated Skin by Catalase InductionTaxifolin suppresses UV-induced skin carcinogenesis by targeting EGFR and PI3K.Keratinocyte apoptosis in epidermal development and disease.Genetic ablation of cyclooxygenase-2 in keratinocytes produces a cell-autonomous defect in tumor formation.RSK2 as a key regulator in human skin cancer.Osteopontin expression in normal skin and non-melanoma skin tumors.The aryl hydrocarbon receptor and light.The epidermal growth factor receptor increases cytokine production and cutaneous inflammation in response to ultraviolet irradiation.Egr1 regulates the coordinated expression of numerous EGF receptor target genes as identified by ChIP-on-chipWaveband and dose dependency of sunlight-induced immunomodulation and cellular changes.A Rising Cancer Prevention Target of RSK2 in Human Skin Cancer.Erbb2 suppresses DNA damage-induced checkpoint activation and UV-induced mouse skin tumorigenesis.Requirement for metalloproteinase-dependent ERK and AKT activation in UVB-induced G1-S cell cycle progression of human keratinocytes.The prostaglandin receptor EP2 activates multiple signaling pathways and beta-arrestin1 complex formation during mouse skin papilloma developmentThe epidermal growth factor receptor in squamous cell carcinoma: An emerging drug target.The roles of vitamin D in seborrhoeic keratosis: possible genetic and cellular signalling mechanisms.Targeted therapy in nonmelanoma skin cancers.Epidermal growth factor receptor signalling in keratinocyte biology: implications for skin toxicity of tyrosine kinase inhibitors.Manganese superoxide dismutase-mediated inside-out signaling in HaCaT human keratinocytes and SKH-1 mouse skin.Soluble E-cadherin: a critical oncogene modulating receptor tyrosine kinases, MAPK and PI3K/Akt/mTOR signaling.Human keratinocytes acquire cellular cytotoxicity under UV-B irradiation. Implication of granzyme B and perforin.Epidermal growth factor receptor expression in mice skin upon ultraviolet B exposure - Seborrheic Keratosis as a coincidental and unique finding.EGFR inhibitors, MHC expression and immune responses : Can EGFR inhibitors be used as immune response modifiers?Akt1-mediated intracellular oxidation after UVB irradiation suppresses apoptotic cell death induced by cell detachment and serum starvation.Gefitinib for patients with incurable cutaneous squamous cell carcinoma: A single-arm phase II clinical trial.Induction of Tyrosine Phosphorylation of UV-Activated EGFR by the Beta-Human Papillomavirus Type 8 E6 Leads to Papillomatosis.RhoB protects human keratinocytes from UVB-induced apoptosis through epidermal growth factor receptor signaling.Targeted Therapies: Immunologic Effects and Potential Applications Outside of Cancer.Induction of ErbB2 by ultraviolet A irradiation: potential role in malignant transformation of keratinocytes.Commentary to Pastore et al. (2014): epidermal growth factor receptor signaling in keratinocyte biology: implications for skin toxicity of tyrosine kinase inhibitors.
P2860
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P2860
Chemoprevention of UV light-induced skin tumorigenesis by inhibition of the epidermal growth factor receptor.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Chemoprevention of UV light-in ...... dermal growth factor receptor.
@en
Chemoprevention of UV light-in ...... dermal growth factor receptor.
@nl
type
label
Chemoprevention of UV light-in ...... dermal growth factor receptor.
@en
Chemoprevention of UV light-in ...... dermal growth factor receptor.
@nl
prefLabel
Chemoprevention of UV light-in ...... dermal growth factor receptor.
@en
Chemoprevention of UV light-in ...... dermal growth factor receptor.
@nl
P2093
P1433
P1476
Chemoprevention of UV light-in ...... dermal growth factor receptor.
@en
P2093
Carol Trempus
Igor Shendrik
Jill Fuhrman
Laura A Hansen
Raymond W Tennant
Taghrid B El-Abaseri
P304
P356
10.1158/0008-5472.CAN-04-2204
P407
P577
2005-05-01T00:00:00Z