Overexpression of the aldo-keto reductase family protein AKR1B10 is highly correlated with smokers' non-small cell lung carcinomas.
about
Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoidsAldo-keto reductase family 1 B10 affects fatty acid synthesis by regulating the stability of acetyl-CoA carboxylase-alpha in breast cancer cellsStructural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug designStructural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10Aldo-Keto Reductases 1B in Adrenal Cortex PhysiologyGenome-wide and differential proteomic analysis of hepatitis B virus and aflatoxin B1 related hepatocellular carcinoma in Guangxi, ChinaHuman aldo-keto reductases and the metabolic activation of polycyclic aromatic hydrocarbonsThe Role of Human Aldo-Keto Reductases in the Metabolic Activation and Detoxication of Polycyclic Aromatic Hydrocarbons: Interconversion of PAH Catechols and PAH o-QuinonesEvidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cellsEffect of active smoking on the human bronchial epithelium transcriptome.Transcriptome profiles of carcinoma-in-situ and invasive non-small cell lung cancer as revealed by SAGEGene expression profiling of metaplastic lineages identifies CDH17 as a prognostic marker in early stage gastric cancer.Expression of aldo-keto reductase family 1 member b10 in the early stages of human hepatocarcinogenesisAldo-Keto Reductase Family 1 Member B10 Inhibitors: Potential Drugs for Cancer Treatment.Quantitation of mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites in a smoking cessation studyAKR1B10 promotes breast cancer cell migration and invasion via activation of ERK signalingViral expression and molecular profiling in liver tissue versus microdissected hepatocytes in hepatitis B virus-associated hepatocellular carcinoma.Impact of smoking cessation on global gene expression in the bronchial epithelium of chronic smokers.Smoking-induced upregulation of AKR1B10 expression in the airway epithelium of healthy individuals.Molecular analysis of thymoma.High expression of aldo-keto reductase 1B10 is an independent predictor of favorable prognosis in patients with hepatocellular carcinomaGene expression profiling unravels cancer-related hepatic molecular signatures in steatohepatitis but not in steatosisVitamin C supplementation lowers urinary levels of 4-hydroperoxy-2-nonenal metabolites in humansHuman aldo-keto reductases: Function, gene regulation, and single nucleotide polymorphisms.Human and rodent aldo-keto reductases from the AKR1B subfamily and their specificity with retinaldehyde.AKR1B10 induces cell resistance to daunorubicin and idarubicin by reducing C13 ketonic group.Quantitative evaluation of aldo-keto reductase expression in hepatocellular carcinoma (HCC) cell lines.Impaired self-renewal and increased colitis and dysplastic lesions in colonic mucosa of AKR1B8-deficient mice.Side population cells of pancreatic cancer show characteristics of cancer stem cells responsible for resistance and metastasis.The aldo-keto reductases (AKRs): Overview.Novel chemical scaffolds of the tumor marker AKR1B10 inhibitors discovered by 3D QSAR pharmacophore modeling.Enzymes of the AKR1B and AKR1C Subfamilies and Uterine Diseases.Biological role of aldo-keto reductases in retinoic Acid biosynthesis and signaling.Aldo-Keto Reductases 1B in Endocrinology and Metabolism.Identification of retinoic acid as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.In-depth proteomic analysis of nonsmall cell lung cancer to discover molecular targets and candidate biomarkers.Regulation of aldo-keto-reductase family 1 B10 by 14-3-3ε and their prognostic impact of hepatocellular carcinoma.Comparison of p53 mutations induced by PAH o-quinones with those caused by anti-benzo[a]pyrene diol epoxide in vitro: role of reactive oxygen and biological selection.Low expression of Aldo-keto reductase 1B10 is a novel independent prognostic indicator for nasopharyngeal carcinoma.
P2860
Q24294264-C23EDBC0-B944-4F87-B98C-3E6C133CAB6FQ24302032-097BE97B-87F7-4285-ACFC-296750F2A663Q27649354-9AAB0DD9-7D93-491F-A873-7705E4C96764Q27689445-0E019D98-79EB-42F0-AEE4-EFBF55A78728Q27702584-61DE42D7-0ADB-4503-BA81-8391B62C9FDEQ28078668-284CFB61-0B47-47E2-84C5-3D31A6FC705EQ28538135-6F5141E6-C44B-4777-A8DE-D5F7E8968E7EQ28651791-70B46907-72E0-4BE1-9322-39D38FD833ADQ28712007-13A0CE7E-03B4-45F2-A13E-2C7C9F16B7A1Q28754574-D65D9C56-8546-4CC5-BE2A-F0B3E9430A18Q33295454-5DE080F4-D57E-4C4F-B9D1-8374C4AAC319Q33531797-E0D6C0ED-EC43-4AFC-95DB-B49EDEEBC49FQ33557996-32A8B961-592D-4D42-8BDF-35CDB0940DAEQ33580721-FBBAB0C6-2F42-44E3-A36D-4B76851D92B1Q33600379-8E4C7910-00AF-48C2-BEDD-2C48B7256BBFQ33636867-BE23FD1A-FAE4-42F7-A180-2C8A0E641035Q33779639-006EED72-8768-4503-9E68-126F62871EEEQ34079748-CF22A9AE-CBC1-4995-99CE-F83F977626EDQ34273137-CDC13C26-984E-4B5D-A63B-C846CF5305ECQ34386382-5819D4D1-945A-4DE5-BFCB-3891CCA7D6BCQ34388819-4099BD0D-1F8F-47B9-B8D5-3B57C7165979Q34432183-BFF1429D-A735-4BBD-8E4F-AAB08A7422E6Q34447251-FDD4B006-58ED-464F-818A-8B968390AF6BQ34612898-BE430A1A-D45F-43C4-BFD4-935394F42BC8Q34632786-0A15FE1A-BBD7-4F2B-A1C6-4BE8853706FBQ35012097-FD28B085-031A-4A73-AC6F-BA9B823405C3Q35141326-605B935D-796A-4A8C-AFEE-E444677A1568Q35171770-B2054151-9C97-4F22-802D-25880AEB37A4Q35178414-8115F3E6-8EBF-42C9-91B3-46EE21798CFFQ35192383-41030698-F5B6-407F-8431-8934591E1C1BQ35305934-63ECA3F3-8CB8-4D06-AF93-FCA963FEC32AQ35655693-4F8E736C-DBA3-4CDB-9F95-ADB6D56DE935Q35825211-51C6EB2B-55E7-4ECA-AE5E-55B2411E3E6DQ35893754-1EE417E0-17C3-4A64-8090-31446D1D43D3Q36135903-8ADADAB9-254E-4901-9208-5553B41AA638Q36288735-4C5D61F5-E2F7-467B-8A5D-45298A2F6123Q36386730-1348E116-AB49-462D-BA56-7408A0245310Q36629475-648D3857-3212-4A4D-8C15-8FAEDE94920EQ36631263-FA76B047-4674-41EE-B864-602BD0A47347Q36654211-25159020-49D9-4247-8A4E-18DB26BD415D
P2860
Overexpression of the aldo-keto reductase family protein AKR1B10 is highly correlated with smokers' non-small cell lung carcinomas.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Overexpression of the aldo-ket ...... on-small cell lung carcinomas.
@en
Overexpression of the aldo-ket ...... on-small cell lung carcinomas.
@nl
type
label
Overexpression of the aldo-ket ...... on-small cell lung carcinomas.
@en
Overexpression of the aldo-ket ...... on-small cell lung carcinomas.
@nl
prefLabel
Overexpression of the aldo-ket ...... on-small cell lung carcinomas.
@en
Overexpression of the aldo-ket ...... on-small cell lung carcinomas.
@nl
P2093
P1476
Overexpression of the aldo-ket ...... on-small cell lung carcinomas.
@en
P2093
Akira Watanabe
Hirokazu Taniguchi
Hiroko Iwanari
Hirotaka Ito
Hirotoshi Dosaka-Akita
Hiroyuki Aburatani
Hisashi Moriguchi
Junji Shibahara
Masashi Fukayama
Mitsugu Hironaka
P304
P356
10.1158/1078-0432.CCR-04-1238
P407
P577
2005-03-01T00:00:00Z