Inactivation of both alleles of the DPC4/SMAD4 gene in advanced colorectal cancers: identification of seven novel somatic mutations in tumors from Japanese patients.
about
C8orf4 is a transforming growth factor B induced transcript downregulated in metastatic colon cancerStructural basis for the cooperative DNA recognition by Smad4 MH1 dimersEpidermal growth factor receptor signaling pathway is frequently altered in ampullary carcinoma at protein and genetic levels.SMAD4--molecular gladiator of the TGF-beta signaling is trampled upon by mutational insufficiency in colorectal carcinoma of Kashmiri population: an analysis with relation to KRAS proto-oncogene.SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathwayCooperative assembly of Co-Smad4 MH1 with R-Smad1/3 MH1 on DNA: a molecular dynamics simulation studyIdentification of the modifier of Min 2 (Mom2) locus, a new mutation that influences Apc-induced intestinal neoplasia.The angiogenic switch molecule, secreted FGF-binding protein, an indicator of early stages of pancreatic and colorectal adenocarcinoma.Loss of Dpc4 expression in colonic adenocarcinomas correlates with the presence of metastatic disease.Development and progression of colorectal neoplasia.Tumor angiogenesis: initiation and targeting - therapeutic targeting of an FGF-binding protein, an angiogenic switch molecule, and indicator of early stages of gastrointestinal adenocarcinomas -Inhibition of pancreatic carcinoma cell growth in vitro by DPC4 gene transfection.Next generation sequencing and a new era of medicine.Prognostic value of loss of heterozygosity and sub-cellular localization of SMAD4 varies with tumor stage in colorectal cancer.Functional mapping of the MH1 DNA-binding domain of DPC4/SMAD4.Effect of deleted pancreatic cancer locus 4 gene transfection on biological behaviors of human colorectal carcinoma cells.No SMAD4 hypermethylation in colorectal cancer.Frequent loss of SMAD4/DPC4 protein in colorectal cancers.Frequent loss of SMAD4/DPC4 protein in colorectal cancers.Loss of heterozygosity on chromosome 10p14-p15 in colorectal carcinoma.Analysis of SMAD4/DPC4 gene alterations in multiploid colorectal carcinomas.Epithelial to mesenchymal transition in colorectal cancer
P2860
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P2860
Inactivation of both alleles of the DPC4/SMAD4 gene in advanced colorectal cancers: identification of seven novel somatic mutations in tumors from Japanese patients.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Inactivation of both alleles o ...... tumors from Japanese patients.
@en
Inactivation of both alleles o ...... tumors from Japanese patients.
@nl
type
label
Inactivation of both alleles o ...... tumors from Japanese patients.
@en
Inactivation of both alleles o ...... tumors from Japanese patients.
@nl
prefLabel
Inactivation of both alleles o ...... tumors from Japanese patients.
@en
Inactivation of both alleles o ...... tumors from Japanese patients.
@nl
P2093
P1433
P1476
Inactivation of both alleles o ...... tumors from Japanese patients.
@en
P2093
P356
10.1016/S1383-5726(99)00003-5
P407
P577
1999-08-01T00:00:00Z