The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator. - Wikidata - wikimedia - TriplyDB

The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator.

The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator.

http://www.wikidata.org/entity/Q53453365

about

Emerging Functions of RANKL in Lymphoid Tissues Expression of the autoimmune regulator gene and its relevance to the mechanisms of central and peripheral tolerance Aire and T cell development Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4 Transcriptional regulation by AIRE: molecular mechanisms of central tolerance Control of the thymic medulla and its influence on αβT-cell development Positive and Negative Regulatory Mechanisms for Fine-Tuning Cellularity and Functions of Medullary Thymic Epithelial Cells Thymic B Cells and Central T Cell Tolerance Thymic Crosstalk Coordinates Medulla Organization and T-Cell Tolerance Induction Thymic epithelial cell development and differentiation: cellular and molecular regulation Antigen recognition by autoreactive CD4⁺ thymocytes drives homeostasis of the thymic medulla Identification of novel thymic epithelial cell subsets whose differentiation is regulated by RANKL and Traf6 Adult thymic epithelial cell (TEC) progenitors and TEC stem cells: Models and mechanisms for TEC development and maintenance RANKL/RANK-beyond bones Deficiency of the metalloproteinase-disintegrin ADAM8 is associated with thymic hyper-cellularity RANKL Is Necessary and Sufficient to Initiate Development of Antigen-Sampling M Cells in the Intestinal Epithelium T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction.DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration.Enhancement of an anti-tumor immune response by transient blockade of central T cell tolerance.Exploring codon optimization and response surface methodology to express biologically active transmembrane RANKL in E. coli.Intrathymic transplantation of bone marrow-derived progenitors provides long-term thymopoiesis.ADAM17 deletion in thymic epithelial cells alters aire expression without affecting T cell developmental progression Thymic homing of activated CD4+ T cells induces degeneration of the thymic epithelium through excessive RANK signaling.Administration of RANKL boosts thymic regeneration upon bone marrow transplantation Roles of the NF-kappaB pathway in lymphocyte development and function.Regulation of medullary thymic epithelial cell differentiation and function by the signaling protein Sin.Cutting edge: Antigen-specific thymocyte feedback regulates homeostatic thymic conventional dendritic cell maturation.Rare development of Foxp3+ thymocytes in the CD4+CD8+ subset Selective targeting of RANK signaling pathways as new therapeutic strategies for osteoporosis.Direct and indirect roles of the LTbetaR pathway in central tolerance induction.Control of central and peripheral tolerance by Aire.Molecular and cellular basis of T cell lineage commitment.DNA methylation profile of Aire-deficient mouse medullary thymic epithelial cells Limitation of immune tolerance-inducing thymic epithelial cell development by Spi-B-mediated negative feedback regulation T cell-B cell thymic cross-talk: maintenance and function of thymic B cells requires cognate CD40-CD40 ligand interaction.Established thymic epithelial progenitor/stem cell-like cell lines differentiate into mature thymic epithelial cells and support T cell development.Abnormalities of thymic stroma may contribute to immune dysregulation in murine models of leaky severe combined immunodeficiency.Resident B cells regulate thymic expression of myelin oligodendrocyte glycoprotein.Commensal bacteria regulate thymic Aire expression NF-κB in immunobiology.

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P2860

The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator.

http://www.wikidata.org/entity/Q53453365

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

The cytokine RANKL produced by ...... express autoimmune regulator.

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The cytokine RANKL produced by ...... express autoimmune regulator.

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type

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The cytokine RANKL produced by ...... express autoimmune regulator.

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The cytokine RANKL produced by ...... express autoimmune regulator.

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The cytokine RANKL produced by ...... express autoimmune regulator.

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J.IMMUNI.2008.06.018

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The cytokine RANKL produced by ...... express autoimmune regulator.

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Hiroshi Takayanagi

http://www.w3.org/2001/XMLSchema#string

Hisakata Yamada

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Izumi Ohigashi

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Jun-Ichiro Inoue

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Kouta Yano

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Mitsuru Matsumoto

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Naozumi Ishimaru

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Takeshi Nitta

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Yasunobu Yoshikai

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Yoshifumi Yokota

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438-450

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scholarly article

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10.1016/J.IMMUNI.2008.06.018

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3

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Josef M Penninger

Taishin Akiyama

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23263229

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18799150

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