Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.
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The role of "mixed" orexigenic and anorexigenic signals and autoantibodies reacting with appetite-regulating neuropeptides and peptides of the adipose tissue-gut-brain axis: relevance to food intake and nutritional status in patients with anorexia nRecent advances in understanding the anti-diabetic actions of dietary flavonoidsObestatin: a new metabolic player in the pancreas and white adipose tissueGrowth hormone-releasing hormone promotes survival of cardiac myocytes in vitro and protects against ischaemia-reperfusion injury in rat heartCombination of Selective Immunoassays and Mass Spectrometry to Characterize Preproghrelin-Derived Peptides in Mouse TissuesObestatin induction of early-response gene expression in gastrointestinal and adipose tissues and the mediatory role of G protein-coupled receptor, GPR39Obestatin stimulates glucose-induced insulin secretion through ghrelin receptor GHS-R.Neural and hormonal regulation of pancreatic secretion.Treatment with recombinant tumor necrosis factor-related apoptosis-inducing ligand alleviates the severity of streptozotocin-induced diabetesReceptors and effects of gut hormones in three osteoblastic cell linesThe gut hormone ghrelin partially reverses energy substrate metabolic alterations in the failing heart.Agonist of growth hormone-releasing hormone as a potential effector for survival and proliferation of pancreatic isletsIntegrating GHS into the Ghrelin System.The ghrelin gene products and exendin-4 promote survival of human pancreatic islet endothelial cells in hyperglycaemic conditions, through phosphoinositide 3-kinase/Akt, extracellular signal-related kinase (ERK)1/2 and cAMP/protein kinase A (PKA) siGhrelin gene products in acute and chronic inflammation.AMPK as Target for Intervention in Childhood and Adolescent ObesityGhrelin-related peptides exert protective effects in the cerebral circulation of male mice through a nonclassical ghrelin receptor(s).Obestatin enhances in vitro generation of pancreatic islets through regulation of developmental pathways.Cyclic AMP is both a pro-apoptotic and anti-apoptotic second messengerGenistein ameliorates hyperglycemia in a mouse model of nongenetic type 2 diabetes.Inducible nitric-oxide synthase and nitric oxide donor decrease insulin receptor substrate-2 protein expression by promoting proteasome-dependent degradation in pancreatic beta-cells: involvement of glycogen synthase kinase-3beta.Ablation of ghrelin receptor in leptin-deficient ob/ob mice has paradoxical effects on glucose homeostasis when compared with ablation of ghrelin in ob/ob mice.Obestatin induced recovery of myocardial dysfunction in type 1 diabetic rats: underlying mechanismsEffect of Helicobacter pylori eradication on serum ghrelin and obestatin levels.Small molecule kaempferol modulates PDX-1 protein expression and subsequently promotes pancreatic β-cell survival and function via CREB.Obestatin as a key regulator of metabolism and cardiovascular function with emerging therapeutic potential for diabetes.Treatment of lean and diet-induced obesity (DIO) mice with a novel stable obestatin analogue alters plasma metabolite levels as detected by untargeted LC-MS metabolomicsObestatin as a regulator of adipocyte metabolism and adipogenesis.Obestatin plays an opposite role in the regulation of pituitary somatotrope and corticotrope function in female primates and male/female mice.Biological effects of obestatin.Cardiovascular actions of the ghrelin gene-derived peptides and growth hormone-releasing hormone.Obestatin: an interesting but controversial gut hormone.Role of SST, CORT and ghrelin and its receptors at the endocrine pancreas.The role of obestatin in roux-en-Y gastric bypass-induced remission of type 2 diabetes mellitus.Obestatin controls skeletal muscle fiber-type determination.Chemosensory signalling pathways involved in sensing of amino acids by the ghrelin cellProtection of MES23.5 dopaminergic cells by obestatin is mediated by proliferative rather than anti-apoptotic action.Proteomic study on the protective mechanism of fibroblast growth factor 21 to ischemia-reperfusion injury.The obestatin/GPR39 system is up-regulated by muscle injury and functions as an autocrine regenerative system.Obestatin Accelerates the Healing of Acetic Acid-Induced Colitis in Rats.
P2860
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P2860
Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Obestatin promotes survival of ...... f beta-cell mass and function.
@en
Obestatin promotes survival of ...... f beta-cell mass and function.
@nl
type
label
Obestatin promotes survival of ...... f beta-cell mass and function.
@en
Obestatin promotes survival of ...... f beta-cell mass and function.
@nl
prefLabel
Obestatin promotes survival of ...... f beta-cell mass and function.
@en
Obestatin promotes survival of ...... f beta-cell mass and function.
@nl
P2093
P50
P356
P1433
P1476
Obestatin promotes survival of ...... of beta-cell mass and function
@en
P2093
Corrado Ghè
Davide Gallo
Elisa Arnoletti
Ezio Ghigo
Fabio Settanni
Luigi Biancone
Marco Volante
Marta Annunziata
Mauro Papotti
P304
P356
10.2337/DB07-1104
P407
P577
2007-12-27T00:00:00Z