Skp2 controls adipocyte proliferation during the development of obesity.
about
Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progressionOverexpression of KLF15 transcription factor in adipocytes of mice results in down-regulation of SCD1 protein expression in adipocytes and consequent enhancement of glucose-induced insulin secretionGenetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligasesPossible involvement of Opa-interacting protein 5 in adipose proliferation and obesityMesoderm-specific transcript is associated with fat mass expansion in response to a positive energy balanceRMI1 deficiency in mice protects from diet and genetic-induced obesityAdipocyte hyperplasia and RMI1 in the treatment of obesity.The early nutritional environment of mice determines the capacity for adipose tissue expansion by modulating genes of caveolae structure.Ablation of 3-phosphoinositide-dependent protein kinase 1 (PDK1) in vascular endothelial cells enhances insulin sensitivity by reducing visceral fat and suppressing angiogenesis.Global transcriptome profiling identifies KLF15 and SLC25A10 as modifiers of adipocytes insulin sensitivity in obese womenDifferential roles of CIDEA and CIDEC in insulin-induced anti-apoptosis and lipid droplet formation in human adipocytes.Adipose tissue-specific dysregulation of angiotensinogen by oxidative stress in obesity.Effects of Kurozu concentrated liquid on adipocyte size in rats.Roles of F-box proteins in cancerDifferential regulation of CIDEA and CIDEC expression by insulin via Akt1/2- and JNK2-dependent pathways in human adipocytesDiet-induced obesity in stem cell antigen-1 KO mice.Cyclin-dependent kinase inhibitor, p21WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance.Essential role of Skp2-mediated p27 degradation in growth and adaptive expansion of pancreatic beta cells.Long-term dietary supplementation with saury oil attenuates metabolic abnormalities in mice fed a high-fat diet: combined beneficial effect of omega-3 fatty acids and long-chain monounsaturated fatty acids.A pathway-based analysis on the effects of obstructive sleep apnea in modulating visceral fat transcriptome.A novel JNK2/SREBP-1c pathway involved in insulin-induced fatty acid synthesis in human adipocytes.Using a novel coculture model to dissect the role of intramuscular lipid load on skeletal muscle insulin responsiveness under reduced estrogen conditions.The FoxO transcription factors and metabolic regulation.Targeting ubiquitination for cancer therapies.Flow cytometric and immunohistochemical detection of in vivo BrdU-labeled cells in mouse fat depots.Tissue-specificity and ethnic diversity in obesity-related risk of cancer may be explained by variability in insulin response and insulin signaling pathways.Telmisartan ameliorates insulin sensitivity by activating the AMPK/SIRT1 pathway in skeletal muscle of obese db/db mice.Curcumin Inhibits 3T3-L1 Preadipocyte Proliferation by Mechanisms Involving Post-transcriptional p27 Regulation.Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist.Depot-specific differences in fat mass expansion in WT and ob/ob mice.Akt-dependent Skp2 mRNA translation is required for exiting contact inhibition, oncogenesis, and adipogenesis.Natriuretic peptides/cGMP/cGMP-dependent protein kinase cascades promote muscle mitochondrial biogenesis and prevent obesity.Skp2: a dream target in the coming age of cancer therapy.Soluble soy protein peptic hydrolysate stimulates adipocyte differentiation in 3T3-L1 cells.Stemness and osteogenic and adipogenic potential are differently impaired in subcutaneous and visceral adipose derived stem cells (ASCs) isolated from obese donors.The Role of Heparin Cofactor Ⅱ in the Regulation of Insulin Sensitivity and Maintenance of Glucose Homeostasis in Humans and Mice.Subcutaneous adipose tissue gene expression and DNA methylation respond to both short- and long-term weight loss.Depot- and gender-specific expression of NLRP3 inflammasome and toll-like receptors in adipose tissue of cancer patients.Recruitment of fat cell precursors during high fat diet in C57BL/6J mice is fat depot specific.MicroRNA-129-5p inhibits 3T3-L1 preadipocyte proliferation by targeting G3BP1
P2860
Q24314416-1CBE9858-A3A7-4AF4-B30C-7F9677682340Q24634769-3DA15F34-7655-47C0-A4B5-2E847AE89C6DQ27027897-79179A10-35B9-45A2-B3DE-25B68AA632A4Q27324265-6C17103E-BD3A-46FF-9C85-6CA281BDD176Q28506024-DCB03BBF-6AB2-4191-BC98-251E5774C070Q28592051-A3748F58-07B7-4C76-A551-A5555733F77BQ30398044-DA79A9B3-3721-4583-BA52-07A47151F652Q33614647-87DE0476-F15F-45EF-91F2-E2FB07100E93Q33636706-3E0FB15F-0DBC-4355-8D3C-697A9DA81BD6Q33751803-A769F8E5-1A7C-49A3-AC90-BB8CE757D530Q33901948-9D435BD8-3C87-4573-B7EF-D731F231842FQ33936984-ABA257E9-DF5F-4B99-8D5E-C0AB2A12660CQ34410508-C3C2ED06-E1FB-4D1E-A11A-39F440FCEA3CQ35012352-2A364626-BA35-4F49-AD3A-376EC287374BQ35107276-EF15D427-DE7A-43DA-959F-019EFEA0D759Q35673110-5894BDB4-D0B4-4A42-BC73-C5B897039D49Q35674559-CB125C11-1A96-43F8-AB9E-188455BAD74BQ35970911-4254AD59-EB06-4A90-BB41-C0C613F8CE9FQ36337183-8B8AC77D-A7A5-4E49-8D30-9765CDBF621AQ36473127-50A4F0F5-5C16-4879-B983-14325F92541FQ36822543-97F4E6A7-BFAA-4BE6-8AC8-E557D0A02B97Q36923620-F97B99F8-56A1-49EC-988D-DD9EED6F6A7CQ37005651-211E229E-16D7-410B-AB88-42CB8A9D9928Q37158445-F2DB5B11-FAB3-4D37-AB7B-3533E791AFECQ37317354-1FC883B3-DD36-45F1-A942-5DA7DAB006B9Q37691234-C01C33D8-6CDC-4A4D-BC7E-E4E7DADABDBBQ39247798-D7FEE6C7-87A6-4589-BDE6-AF30E5D52EB1Q40187380-869256D8-DF58-4ADB-8C76-0F30C1CB6CAAQ40237087-2D2262B8-5DEA-41F6-A8AA-C22926C15FE1Q41234138-E21F3115-0457-4231-A8D3-AA7AA5D63649Q41865466-53F52304-B81B-4919-8DF6-79EB9C689E3CQ41886648-66FD06BB-6937-4311-9A6C-0C3D9A4D9A15Q42366668-EEBD51A2-7D67-4256-88E1-C1F4170EBFC5Q42824775-AC55ADA9-714D-403A-9433-394A2437803DQ43642407-49111636-BC0E-4C60-A98D-EB9A1E7EE5D5Q47142701-D4E053C5-AFFE-4250-9A42-B31BCD895928Q47183937-B59F092B-93D0-4CFA-BDC2-65007F2333E4Q50907963-C0FB76EA-E955-4782-A3DF-741C2D8F5824Q55345438-AED28BEB-A7BC-44CC-A814-F2A2225F2F68Q58247057-7CE1D221-0650-4390-9346-4DF90BC44E51
P2860
Skp2 controls adipocyte proliferation during the development of obesity.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Skp2 controls adipocyte proliferation during the development of obesity.
@en
Skp2 controls adipocyte proliferation during the development of obesity.
@nl
type
label
Skp2 controls adipocyte proliferation during the development of obesity.
@en
Skp2 controls adipocyte proliferation during the development of obesity.
@nl
prefLabel
Skp2 controls adipocyte proliferation during the development of obesity.
@en
Skp2 controls adipocyte proliferation during the development of obesity.
@nl
P2093
P2860
P356
P1476
Skp2 controls adipocyte proliferation during the development of obesity.
@en
P2093
Eijiro Watanabe
Hiroshi Sakaue
Keiichi I Nakayama
Keiko Nakayama
Masato Kasuga
Mitsuru Okada
Ryuji Hiramatsu
Takehiro Nakamura
Tamon Sakai
Yasushi Matsuki
P2860
P304
P356
10.1074/JBC.M608144200
P407
P577
2006-11-02T00:00:00Z