Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway. - Wikidata - wikimedia - TriplyDB

Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway.

Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway.

http://www.wikidata.org/entity/Q53600237

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Melanoma: from melanocyte to genetic alterations and clinical options Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence Remodeling of chromatin structure in senescent cells and its potential impact on tumor suppression and aging The thioxotriazole copper(II) complex A0 induces endoplasmic reticulum stress and paraptotic death in human cancer cells "Inflammaging" as a Druggable Target: A Senescence-Associated Secretory Phenotype-Centered View of Type 2 Diabetes Cancer Microenvironment and Endoplasmic Reticulum Stress Response Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells.TMEM33: a new stress-inducible endoplasmic reticulum transmembrane protein and modulator of the unfolded protein response signaling Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death PERK Integrates Oncogenic Signaling and Cell Survival During Cancer Development Kaposi's sarcoma-associated herpesvirus K7 induces viral G protein-coupled receptor degradation and reduces its tumorigenicity Induction of premature senescence by hsp90 inhibition in small cell lung cancer RPLP1, a crucial ribosomal protein for embryonic development of the nervous system Tumorigenic and Immunosuppressive Effects of Endoplasmic Reticulum Stress in Cancer Principles of cancer therapy: oncogene and non-oncogene addiction AGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and D RAB7 counteracts PI3K-driven macropinocytosis activated at early stages of melanoma development Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers.A stromal gene signature associated with inflammatory breast cancer.Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner.Inhibition of proliferation by PERK regulates mammary acinar morphogenesis and tumor formation.Ras, an actor on many stages: posttranslational modifications, localization, and site-specified events.Inhibition of eIF2alpha dephosphorylation inhibits ErbB2-induced deregulation of mammary acinar morphogenesis The relative contributions of the p53 and pRb pathways in oncogene-induced melanocyte senescence.Dormancy of metastatic melanoma New biomarkers probing depth of cell senescence assessed by laser scanning cytometry.SNIPER(TACC3) induces cytoplasmic vacuolization and sensitizes cancer cells to Bortezomib.The nuclear receptor peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) promotes oncogene-induced cellular senescence through repression of endoplasmic reticulum stress.PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage Oncogenic stress induced by acute hyper-activation of Bcr-Abl leads to cell death upon induction of excessive aerobic glycolysis.Combining the endoplasmic reticulum stress-inducing agents bortezomib and fenretinide as a novel therapeutic strategy for metastatic melanoma Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress.Raf/MEK/ERK can regulate cellular levels of LC3B and SQSTM1/p62 at expression levels Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis.The essence of senescence.Differential sensitization of different prostate cancer cells to apoptosis.Ubiquitination of inositol-requiring enzyme 1 (IRE1) by the E3 ligase CHIP mediates the IRE1/TRAF2/JNK pathway.A high-content screening assay for small-molecule modulators of oncogene-induced senescence.Melanoma proliferation and chemoresistance controlled by the DEK oncogene Antagonistic TSC22D1 variants control BRAF(E600)-induced senescence.

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P2860

Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway.

http://www.wikidata.org/entity/Q53600237

description

2006 nî lūn-bûn

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年學術文章

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2006年學術文章

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2006年學術文章

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name

Anti-oncogenic role of the end ...... mutations in the MAPK pathway.

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Anti-oncogenic role of the end ...... mutations in the MAPK pathway.

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type

label

Anti-oncogenic role of the end ...... mutations in the MAPK pathway.

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Anti-oncogenic role of the end ...... mutations in the MAPK pathway.

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prefLabel

Anti-oncogenic role of the end ...... mutations in the MAPK pathway.

@en

Anti-oncogenic role of the end ...... mutations in the MAPK pathway.

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Nature Cell Biology

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Anti-oncogenic role of the end ...... mutations in the MAPK pathway.

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Christophe Denoyelle

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Douglas R Fullen

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George Abou-Rjaily

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Jenny N Pointer

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Lyndon D Su

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Mikhail A Nikiforov

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Monique Verhaegen

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Randal J Kaufman

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Stephen B Gruber

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Timothy M Johnson

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P2860

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

ATF4 degradation relies on a phosphorylation-dependent interaction with the SCF(betaTrCP) ubiquitin ligase

Endoplasmic reticulum stress: cell life and death decisions.

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

Mutations of the BRAF gene in human cancer

Regulated translation initiation controls stress-induced gene expression in mammalian cells

PERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway

The mammalian unfolded protein response

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

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1053-1063

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scholarly article

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10.1038/NCB1471

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10

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8

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Boris C. Bastian

María S Soengas

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2006-09-10T00:00:00Z

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6826877

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16964246

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endoplasmic reticulum