A microtubule-binding domain in dynactin increases dynein processivity by skating along microtubules.
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In vitro reconstitution of a transport complex containing Rab27a, melanophilin and myosin VaMicrotubule cross-linking triggers the directional motility of kinesin-5Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrinAxonal transport: cargo-specific mechanisms of motility and regulationMolecular pathways regulating mitotic spindle orientation in animal cellsDynactin-dependent cortical dynein and spherical spindle shape correlate temporally with meiotic spindle rotation in Caenorhabditis elegansDiffusion of myosin V on microtubules: a fine-tuned interaction for which E-hooks are dispensableA single protofilament is sufficient to support unidirectional walking of dynein and kinesinSpastin's microtubule-binding properties and comparison to kataninDynactin subunit p150(Glued) is a neuron-specific anti-catastrophe factorSte20-like protein kinase SLK (LOSK) regulates microtubule organization by targeting dynactin to the centrosomeThe p25 subunit of the dynactin complex is required for dynein-early endosome interactionIn vitro reconstitution of a highly processive recombinant human dynein complexActivation of cytoplasmic dynein motility by dynactin-cargo adapter complexes.Regulators of the cytoplasmic dynein motorArp11 affects dynein-dynactin interaction and is essential for dynein function in Aspergillus nidulans.Dynactin enhances the processivity of kinesin-2Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends.Trk activation of the ERK1/2 kinase pathway stimulates intermediate chain phosphorylation and recruits cytoplasmic dynein to signaling endosomes for retrograde axonal transportMyosin Va maneuvers through actin intersections and diffuses along microtubules.Regulation of dynactin through the differential expression of p150Glued isoforms.Microtubule plus-end tracking by CLIP-170 requires EB1.Minimal plus-end tracking unit of the cytoplasmic linker protein CLIP-170.Regulation of the processivity and intracellular localization of Saccharomyces cerevisiae dynein by dynactin.Neurodegeneration mutations in dynactin impair dynein-dependent nuclear migration.A nonprocessive class V myosin drives cargo processively when a kinesin- related protein is a passengerTuning microtubule-based transport through filamentous MAPs: the problem of dynein.A mouse neurodegenerative dynein heavy chain mutation alters dynein motility and localization in Neurospora crassa.Dynactin 3D structure: implications for assembly and dynein binding.Autoregulatory mechanism for dynactin control of processive and diffusive dynein transport.Mechanism and regulation of cytoplasmic dyneinProbing interactions between CLIP-170, EB1, and microtubules.Mammalian Kinesin-3 motors are dimeric in vivo and move by processive motility upon release of autoinhibition.Elucidating the genetics and pathology of Perry syndrome.DCTN1 mutations in Perry syndrome.Structural basis for the extended CAP-Gly domains of p150(glued) binding to microtubules and the implication for tubulin dynamics.Cryo electron tomography of herpes simplex virus during axonal transport and secondary envelopment in primary neurons.Disease-associated mutations in the p150(Glued) subunit destabilize the CAP-gly domain.Evolution of the eukaryotic dynactin complex, the activator of cytoplasmic dyneinDrosophila katanin-60 depolymerizes and severs at microtubule defects.
P2860
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P2860
A microtubule-binding domain in dynactin increases dynein processivity by skating along microtubules.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
A microtubule-binding domain i ...... by skating along microtubules.
@en
A microtubule-binding domain i ...... by skating along microtubules.
@nl
type
label
A microtubule-binding domain i ...... by skating along microtubules.
@en
A microtubule-binding domain i ...... by skating along microtubules.
@nl
prefLabel
A microtubule-binding domain i ...... by skating along microtubules.
@en
A microtubule-binding domain i ...... by skating along microtubules.
@nl
P2093
P2860
P356
P1433
P1476
A microtubule-binding domain i ...... by skating along microtubules.
@en
P2093
Nicholas J Quintyne
Stephanie A Lex
Stephen J King
Tara L Culver-Hanlon
P2860
P2888
P304
P356
10.1038/NCB1370
P577
2006-02-12T00:00:00Z
P6179
1033537089