Contrarily to whey and high protein diets, dietary free leucine supplementation cannot reverse the lack of recovery of muscle mass after prolonged immobilization during ageing.
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Reviewing the Effects of L-Leucine Supplementation in the Regulation of Food Intake, Energy Balance, and Glucose HomeostasisThe TWEAK-Fn14 dyad is involved in age-associated pathological changes in skeletal muscleHigh whey protein intake delayed the loss of lean body mass in healthy old rats, whereas protein type and polyphenol/antioxidant supplementation had no effects.REDD2 expression in rat skeletal muscle correlates with nutrient-induced activation of mTORC1: responses to aging, immobilization, and remobilization.Unilateral hindlimb casting induced a delayed generalized muscle atrophy during rehabilitation that is prevented by a whey or a high protein diet but not a free leucine-enriched dietWhey proteins are more efficient than casein in the recovery of muscle functional properties following a casting induced muscle atrophyA dietary supplementation with leucine and antioxidants is capable to accelerate muscle mass recovery after immobilization in adult ratsOral leucine supplementation is sensed by the brain but neither reduces food intake nor induces an anorectic pattern of gene expression in the hypothalamus.Effects of free leucine supplementation and resistance training on muscle strength and functional status in older adults: a randomized controlled trial.Myostatin Activates the Ubiquitin-Proteasome and Autophagy-Lysosome Systems Contributing to Muscle Wasting in Chronic Kidney DiseaseThe mTORC1 signaling repressors REDD1/2 are rapidly induced and activation of p70S6K1 by leucine is defective in skeletal muscle of an immobilized rat hindlimb.Age-related deficits in skeletal muscle recovery following disuse are associated with neuromuscular junction instability and ER stress, not impaired protein synthesis.Disuse-induced muscle wasting.Leucine supplementation improves skeletal muscle regeneration after cryolesion in rats.Nutritional strategies to counteract muscle atrophy caused by disuse and to improve recovery.Comparative effects of whey protein versus L-leucine on skeletal muscle protein synthesis and markers of ribosome biogenesis following resistance exercise.At same leucine intake, a whey/plant protein blend is not as effective as whey to initiate a transient post prandial muscle anabolic response during a catabolic state in mini pigs.The worsening of tibialis anterior muscle atrophy during recovery post-immobilization correlates with enhanced connective tissue area, proteolysis, and apoptosis.Soluble Milk Proteins Improve Muscle Mass Recovery after Immobilization-Induced Muscle Atrophy in Old Rats but Do not Improve Muscle Functional Property Restoration.Supplementation of ketoacids contributes to the up-regulation of the Wnt7a/Akt/p70S6K pathway and the down-regulation of apoptotic and ubiquitin-proteasome systems in the muscle of 5/6 nephrectomised rats.Older Adults Have Delayed Amino Acid Absorption after a High Protein Mixed Breakfast Meal.Muscle wasting and resistance of muscle anabolism: the "anabolic threshold concept" for adapted nutritional strategies during sarcopenia.
P2860
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P2860
Contrarily to whey and high protein diets, dietary free leucine supplementation cannot reverse the lack of recovery of muscle mass after prolonged immobilization during ageing.
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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name
Contrarily to whey and high pr ...... immobilization during ageing.
@en
Contrarily to whey and high pr ...... immobilization during ageing.
@nl
type
label
Contrarily to whey and high pr ...... immobilization during ageing.
@en
Contrarily to whey and high pr ...... immobilization during ageing.
@nl
prefLabel
Contrarily to whey and high pr ...... immobilization during ageing.
@en
Contrarily to whey and high pr ...... immobilization during ageing.
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P2093
P2860
P50
P1476
Contrarily to whey and high pr ...... d immobilization during ageing
@en
P2093
Carole Migné
Hugues Magne
Isabelle Savary-Auzeloux
Marie-Agnès Peyron
P2860
P304
P356
10.1113/JPHYSIOL.2011.226266
P407
P577
2012-02-20T00:00:00Z