Resistance of HIV-infected macrophages to CD8+ T lymphocyte-mediated killing drives activation of the immune system.

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Resistance of HIV-infected macrophages to CD8+ T lymphocyte-mediated killing drives activation of the immune system.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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Resistance of HIV-infected mac ...... tivation of the immune system.

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Resistance of HIV-infected mac ...... tivation of the immune system.

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Resistance of HIV-infected mac ...... tivation of the immune system.

@en

Resistance of HIV-infected mac ...... tivation of the immune system.

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Resistance of HIV-infected mac ...... tivation of the immune system.

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Resistance of HIV-infected mac ...... tivation of the immune system.

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P1476

Resistance of HIV-infected mac ...... ctivation of the immune system

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David R Collins

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Josh Lengieza

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Judy Lieberman

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Kiera L Clayton

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Musie Ghebremichael

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P2860

Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice

Apoptotic killing of HIV-1-infected macrophages is subverted by the viral envelope glycoprotein

T cell exhaustion

Granzyme B triggers a prolonged pressure to die in Bcl-2 overexpressing cells, defining a window of opportunity for effective treatment with ABT-737

High-multiplicity HIV-1 infection and neutralizing antibody evasion mediated by the macrophage-T cell virological synapse.

Granzyme M targets topoisomerase II alpha to trigger cell cycle arrest and caspase-dependent apoptosis.

Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time.

Magnitude and complexity of rectal mucosa HIV-1-specific CD8+ T-cell responses during chronic infection reflect clinical status

Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control.

Macrophages and HIV-1: An Unhealthy Constellation.

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475-486

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scholarly article

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10.1038/S41590-018-0085-3

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English

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Farokh Dotiwala

Bruce D Walker

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2018-04-18T00:00:00Z

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29670239

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6025741

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