The 6-maleimidocaproyl hydrazone derivative of doxorubicin (DOXO-EMCH) is superior to free doxorubicin with respect to cardiotoxicity and mitochondrial damage.
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Cardiomyocyte death in doxorubicin-induced cardiotoxicityA phase 1B/2 study of aldoxorubicin in patients with soft tissue sarcoma.Synthesis of a covalent epirubicin-(C(3)-amide)-anti-HER2/neu immunochemotherapeutic utilizing a UV-photoactivated anthracycline intermediateSynthesis of Gemcitabine-(C4-amide)-[anti-HER2/neu] Utilizing a UV-Photoactivated Gemcitabine Intermediate: Cytotoxic Anti-Neoplastic Activity against Chemotherapeutic-Resistant Mammary Adenocarcinoma SKBr-3.Epirubicin-[Anti-HER2/neu] Synthesized with an Epirubicin-(C13-imino)-EMCS Analog: Anti-Neoplastic Activity against Chemotherapeutic-Resistant SKBr-3 Mammary Carcinoma in Combination with Organic Selenium.Thermal targeting of an acid-sensitive doxorubicin conjugate of elastin-like polypeptide enhances the therapeutic efficacy compared with the parent compound in vivo.Cathepsin B-cleavable doxorubicin prodrugs for targeted cancer therapy (Review)Inauhzin sensitizes p53-dependent cytotoxicity and tumor suppression of chemotherapeutic agents.DOXO-EMCH (INNO-206): the first albumin-binding prodrug of doxorubicin to enter clinical trials.Anticancer carrier-linked prodrugs in clinical trials.Proteins: emerging carrier for delivery of cancer therapeutics.Albumin-Oxanorbornadiene Conjugates Formed ex Vivo for the Extended Circulation of Hydrophilic CargoAnti-cancer effects of novel doxorubicin prodrug PDOX in MCF-7 breast cancer cells.The importance of drug metabolites synthesis: the case-study of cardiotoxic anticancer drugs.Phase I and pharmacokinetic study of the novel anthracycline derivative 5-imino-13-deoxydoxorubicin (GPX-150) in patients with advanced solid tumors.Molecular and Structural Traits of Insulin Receptor Substrate 1/LC3 Nuclear Structures and Their Role in Autophagy Control and Tumor Cell Survival.Aldoxorubicin: a tumor-targeted doxorubicin conjugate for relapsed or refractory soft tissue sarcomas.Aldoxorubicin and Temozolomide combination in a xenograft mice model of human glioblastoma
P2860
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P2860
The 6-maleimidocaproyl hydrazone derivative of doxorubicin (DOXO-EMCH) is superior to free doxorubicin with respect to cardiotoxicity and mitochondrial damage.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
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2007年學術文章
@zh-hant
name
The 6-maleimidocaproyl hydrazo ...... city and mitochondrial damage.
@en
The 6-maleimidocaproyl hydrazone derivative of doxorubicin
@nl
type
label
The 6-maleimidocaproyl hydrazo ...... city and mitochondrial damage.
@en
The 6-maleimidocaproyl hydrazone derivative of doxorubicin
@nl
prefLabel
The 6-maleimidocaproyl hydrazo ...... city and mitochondrial damage.
@en
The 6-maleimidocaproyl hydrazone derivative of doxorubicin
@nl
P2093
P2860
P356
P1476
The 6-maleimidocaproyl hydrazo ...... city and mitochondrial damage.
@en
P2093
Andrea Geist
Bernhard Setzer
Dirk Lebrecht
Felix Kratz
Jörg Haberstroh
Ulrich A Walker
Uwe-Peter Ketelsen
P2860
P304
P356
10.1002/IJC.22409
P577
2007-02-01T00:00:00Z