Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies.

about

Evaluation of the efficacy of dasatinib, a Src/Abl inhibitor, in colorectal cancer cell lines and explant mouse model.ALK Inhibitor Response in Melanomas Expressing EML4-ALK Fusions and Alternate ALK Isoforms.Development of new preclinical models to advance adrenocortical carcinoma research.

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P2860

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies.

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2016 nî lūn-bûn

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Development and Maintenance of ...... f Novel Anti-Cancer Therapies.

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Development and Maintenance of ...... f Novel Anti-Cancer Therapies.

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Development and Maintenance of ...... f Novel Anti-Cancer Therapies.

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Development and Maintenance of ...... f Novel Anti-Cancer Therapies.

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Development and Maintenance of ...... f Novel Anti-Cancer Therapies.

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Development and Maintenance of ...... f Novel Anti-Cancer Therapies.

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Development and Maintenance of ...... of Novel Anti-Cancer Therapies

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P2093

Anna Capasso

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Jihye Kim

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John Arcaroli

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John J Tentler

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Marileila Varella-Garcia

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Peter J Klauck

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S Gail Eckhardt

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Stacey Bagby

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Todd M Pitts

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Wells A Messersmith

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P2860

Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer

Patient-derived tumour xenografts as models for oncology drug development

Patient-derived tumor xenografts: transforming clinical samples into mouse models

Comprehensive molecular characterization of human colon and rectal cancer

Maintaining Tumor Heterogeneity in Patient-Derived Tumor Xenografts

Dual pharmacological targeting of the MAP kinase and PI3K/mTOR pathway in preclinical models of colorectal cancer

A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer.

Potent antitumor activity of cabozantinib, a c-MET and VEGFR2 inhibitor, in a colorectal cancer patient-derived tumor explant model.

A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer.

Cancer statistics, 2015

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scholarly article

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10.3791/54393

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115

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Aik Choon Tan

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2016-09-30T00:00:00Z

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27768028

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xenograft

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5092181

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Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies.

about

P2860

P2860

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies.

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