Novel renin inhibitors containing derivatives of N-alkylleucyl-β-hydroxy-γ-amino acids.

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Novel renin inhibitors containing derivatives of N-alkylleucyl-β-hydroxy-γ-amino acids.

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2016 nî lūn-bûn

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2016年の論文

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年學術文章

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2016年學術文章

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Novel renin inhibitors containing derivatives of N-alkylleucyl-β-hydroxy-γ-amino acids.

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Novel renin inhibitors containing derivatives of N-alkylleucyl-β-hydroxy-γ-amino acids.

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label

Novel renin inhibitors containing derivatives of N-alkylleucyl-β-hydroxy-γ-amino acids.

@en

Novel renin inhibitors containing derivatives of N-alkylleucyl-β-hydroxy-γ-amino acids.

@nl

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Novel renin inhibitors containing derivatives of N-alkylleucyl-β-hydroxy-γ-amino acids.

@en

Novel renin inhibitors containing derivatives of N-alkylleucyl-β-hydroxy-γ-amino acids.

@nl

P1476

Novel renin inhibitors containing derivatives of N-alkylleucyl-β-hydroxy-γ-amino acids.

@en

P2093

Aleksander Paweł Mazurek

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Anna Goldnik

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Daniel Sokulski

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Paweł Jaworski

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P2860

Aliskiren, the first direct renin inhibitor for treatment of hypertension: the path of its development

Structure-based drug design: the discovery of novel nonpeptide orally active inhibitors of human renin

Design and synthesis of potent macrocyclic renin inhibitors

Design and discovery of new (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]piperidine-3-carboxamides as potent renin inhibitors

A novel class of oral direct renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophore

High resolution X-ray analyses of renin inhibitor-aspartic proteinase complexes

Structure-based design of aliskiren, a novel orally effective renin inhibitor

Direct renin inhibitors as a new therapy for hypertension

2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8)

Aliskiren: review of efficacy and safety data with focus on past and recent clinical trials.

P304

106-115

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P31

scholarly article

P356

10.1002/PSC.2846

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Iwona Winiecka

Dorota Marszałek

P577

2016-01-19T00:00:00Z

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P698

26780837

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