Functional design of bacterial mechanosensitive channels. Comparisons and contrasts illuminated by random mutagenesis.
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Two families of mechanosensitive channel proteinsGeneration and evaluation of a large mutational library from the Escherichia coli mechanosensitive channel of large conductance, MscL: implications for channel gating and evolutionary designCysteine scanning of MscL transmembrane domains reveals residues critical for mechanosensitive channel gating.Adaptive behavior of bacterial mechanosensitive channels is coupled to membrane mechanicsThree-dimensional architecture of membrane-embedded MscS in the closed conformationMolecular dynamics study of gating in the mechanosensitive channel of small conductance MscSYbdG in Escherichia coli is a threshold-setting mechanosensitive channel with MscM activityEffects of GsMTx4 on bacterial mechanosensitive channels in inside-out patches from giant spheroplasts.Functional analysis of conserved motifs in the mechanosensitive channel homolog MscS-Like2 from Arabidopsis thaliana.The evolutionary 'tinkering' of MscS-like channels: generation of structural and functional diversity.Genetic screen for potassium leaky small mechanosensitive channels (MscS) in Escherichia coli: recognition of cytoplasmic β domain as a new gating element.Lipid-protein interaction of the MscS mechanosensitive channel examined by scanning mutagenesis.The pathway and spatial scale for MscS inactivation.Expression and characterization of the bacterial mechanosensitive channel MscS in Xenopus laevis oocytesIdentification of mutations that alter the gating of the Escherichia coli mechanosensitive channel protein, MscK.The MscS and MscL families of mechanosensitive channels act as microbial emergency release valves.Characterization of the resting MscS: modeling and analysis of the closed bacterial mechanosensitive channel of small conductance.The "dashpot" mechanism of stretch-dependent gating in MscS.Gain-of-function mutations reveal expanded intermediate states and a sequential action of two gates in MscLInteraction between the cytoplasmic and transmembrane domains of the mechanosensitive channel MscS.Mechanosensitive channel MscS in the open state: modeling of the transition, explicit simulations, and experimental measurements of conductance.AtMSL9 and AtMSL10: Sensors of plasma membrane tension in Arabidopsis rootsMechanosensitivity of ion channels based on protein-lipid interactions.Bacterial mechanosensitive channels--MscS: evolution's solution to creating sensitivity in function.Adaptive MscS gating in the osmotic permeability response in E. coli: the question of time.Plant acoustics: in the search of a sound mechanism for sound signaling in plants.From membrane tension to channel gating: A principal energy transfer mechanism for mechanosensitive channelsIonic regulation of MscK, a mechanosensitive channel from Escherichia coli.Domain organization of the MscS mechanosensitive channel of Escherichia coli.Properties of the Mechanosensitive Channel MscS Pore Revealed by Tryptophan Scanning Mutagenesis.Characterization of three novel mechanosensitive channel activities in Escherichia coli.A gain-of-function mutation in gating of Corynebacterium glutamicum NCgl1221 causes constitutive glutamate secretion.Mutations of the Corynebacterium glutamicum NCgl1221 gene, encoding a mechanosensitive channel homolog, induce L-glutamic acid production.2,2,2-Trifluoroethanol changes the transition kinetics and subunit interactions in the small bacterial mechanosensitive channel MscSTension-activated channels in the mechanism of osmotic fitness in Pseudomonas aeruginosa.C termini of the Escherichia coli mechanosensitive ion channel (MscS) move apart upon the channel opening.Tryptophan in the pore of the mechanosensitive channel MscS: assessment of pore conformations by fluorescence spectroscopy.Pivotal role of the glycine-rich TM3 helix in gating the MscS mechanosensitive channel.Identification and Characterization of the Neisseria gonorrhoeae MscS-like Mechanosensitive Channel.
P2860
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P2860
Functional design of bacterial mechanosensitive channels. Comparisons and contrasts illuminated by random mutagenesis.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Functional design of bacterial ...... minated by random mutagenesis.
@en
Functional design of bacterial ...... minated by random mutagenesis.
@nl
type
label
Functional design of bacterial ...... minated by random mutagenesis.
@en
Functional design of bacterial ...... minated by random mutagenesis.
@nl
prefLabel
Functional design of bacterial ...... minated by random mutagenesis.
@en
Functional design of bacterial ...... minated by random mutagenesis.
@nl
P2093
P2860
P356
P1476
Functional design of bacterial ...... minated by random mutagenesis.
@en
P2093
Kuniyuki Okada
Paul Blount
Paul C Moe
P2860
P304
27682-27688
P356
10.1074/JBC.M202497200
P407
P577
2002-05-15T00:00:00Z