Recombinant human lipocortin 1 inhibits thromboxane release from guinea-pig isolated perfused lung.
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Characterization of cDNA encoding human placental anticoagulant protein (PP4): homology with the lipocortin familyAnnexin proteins PP4 and PP4-X. Comparative characterization of biological activities of placental and recombinant proteinsPrimary structure of the human, membrane-associated Ca2+-binding protein p68 a novel member of a protein familyGlucocorticoid-and non-glucocorticoid induction of lipocortins (annexins) 1 and 2 in rat peritoneal leucocytes in vivoSynthesis and release of platelet-activating factor is inhibited by plasma alpha 1-proteinase inhibitor or alpha 1-antichymotrypsin and is stimulated by proteinasesAnnexin A1 and the Resolution of Inflammation: Modulation of Neutrophil Recruitment, Apoptosis, and ClearanceHuman recombinant lipocortin 1 has acute local anti-inflammatory properties in the rat paw edema test.Dysregulation of anti-inflammatory annexin A1 expression in progressive Crohns DiseaseEvaluation of the antiinflammatory and phospholipase-inhibitory activity of calpactin II/lipocortin I.Eleventh Gaddum memorial lecture. Lipocortin and the mechanism of action of the glucocorticoids.Effect of dexamethasone on neutrophil accumulation and oedema formation in rabbit skin: an investigation of site of action.Differential regulation of 5-lipoxygenase and cyclo-oxygenase pathways of arachidonate metabolism in rat peritoneal leukocytes.Antiinflammatory peptides (antiflammins) inhibit synthesis of platelet-activating factor, neutrophil aggregation and chemotaxis, and intradermal inflammatory reactionsMolecular cloning of murine p68, a Ca2+-binding protein of the lipocortin family.Annexin A1 and the regulation of innate and adaptive immunity.cDNA cloning and tissue-specific regulation of expression of rat calcium-binding protein 65/67. Identification as a homologue of annexin VI.Synthesis of p36 and p35 is increased when U-937 cells differentiate in culture but expression is not inducible by glucocorticoidsThe trans fatty acid elaidate affects the global DNA methylation profile of cultured cells and in vivoAnnexin-A1: a pivotal regulator of the innate and adaptive immune systems.Eicosanoids and platelet-activating factor in allergic respiratory diseases.Exploiting the Annexin A1 pathway for the development of novel anti-inflammatory therapeutics.Glucocorticoid resistance in asthma.Inhibition of O2- generation by dexamethasone is mimicked by lipocortin I in alveolar macrophagesEfficacy and safety of inhaled corticosteroids in asthma. Report of a workshop held in Eze, France, October 1992.An anti-inflammatory protein secreted from the rat seminal vesicle epithelium inhibits the synthesis of platelet-activating factor and the release of arachidonic acid and prostacyclin.Dexamethasone induces the expression of the mRNA of lipocortin 1 and 2 and the release of lipocortin 1 and 5 in differentiated, but not undifferentiated U-937 cells.Monoclonal antibodies to lipocortin-1 as probes for biological function.Lack of involvement of lipocortin 1 in dexamethasone suppression of IL-1 releaseMonoclonal antibodies specific to a Ca2(+)-bound form of lipocortin I distinguish its Ca2(+)-dependent phospholipid-binding ability from its ability to inhibit phospholipase A2.The local anti-inflammatory action of dexamethasone in the rat carrageenin oedema model is reversed by an antiserum to lipocortin 1.Selective inhibition by antiflamrnin-2 of thromboxane B(2) release from isolated and perfused guinea-pig lung.A purified lipocortin shares the anti-inflammatory effect of glucocorticosteroids in vivo in miceA selective antagonist of histamine H₄ receptors prevents antigen-induced airway inflammation and bronchoconstriction in guinea pigs: involvement of lipocortin-1.Expression of human recombinant lipocortin I in a wheat-germ cell-free system and Xenopus oocytes. Lipocortin is not secreted.Glucocorticoid-induced annexin 1 secretion by monocytes and peritoneal leukocytes.Anti-inflammatory actions of an N-terminal peptide from human lipocortin 1.Modulation of phospholipase A2 activity in human fibroblasts.Prevention of endogenous leukotriene production during anaphylaxis in the guinea pig by an inhibitor of leukotriene biosynthesis (MK-886) but not by dexamethasone.Differential modulation of annexin I binding sites on monocytes and neutrophils.Evidence for specific annexin I-binding proteins on human monocytes.
P2860
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P2860
Recombinant human lipocortin 1 inhibits thromboxane release from guinea-pig isolated perfused lung.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
1987年學術文章
@zh-hant
name
Recombinant human lipocortin 1 ...... ea-pig isolated perfused lung.
@en
Recombinant human lipocortin 1 ...... ea-pig isolated perfused lung.
@nl
type
label
Recombinant human lipocortin 1 ...... ea-pig isolated perfused lung.
@en
Recombinant human lipocortin 1 ...... ea-pig isolated perfused lung.
@nl
prefLabel
Recombinant human lipocortin 1 ...... ea-pig isolated perfused lung.
@en
Recombinant human lipocortin 1 ...... ea-pig isolated perfused lung.
@nl
P2093
P356
P1433
P1476
Recombinant human lipocortin 1 ...... ea-pig isolated perfused lung.
@en
P2093
Pepinsky RB
Sinclair LK
P2888
P304
P356
10.1038/328270A0
P407
P577
1987-07-01T00:00:00Z
P6179
1043217493