Rotavirus open cores catalyze 5'-capping and methylation of exogenous RNA: evidence that VP3 is a methyltransferase.
about
Reassignment of specificities of two cap methyltransferase domains in the reovirus lambda 2 proteinpH-Induced Conformational Change of the Rotavirus VP4 Spike: Implications for Cell Entry and Antibody NeutralizationCrystallographic and Biochemical Analysis of Rotavirus NSP2 with Nucleotides Reveals a Nucleoside Diphosphate Kinase-Like ActivityMechanism for Coordinated RNA Packaging and Genome Replication by Rotavirus Polymerase VP1Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase ActivityDetection of novel members, structure-function analysis and evolutionary classification of the 2H phosphoesterase superfamilyIdentification and characterization of a transcription pause site in rotavirus.Mechanism of intraparticle synthesis of the rotavirus double-stranded RNA genome.Predicted structure and domain organization of rotavirus capping enzyme and innate immune antagonist VP3The reversible condensation and expansion of the rotavirus genomeRNA-binding activity of the rotavirus phosphoprotein NSP5 includes affinity for double-stranded RNA.Analysis of a temperature-sensitive mutant rotavirus indicates that NSP2 octamers are the functional form of the protein.De novo synthesis of minus strand RNA by the rotavirus RNA polymerase in a cell-free system involves a novel mechanism of initiation.A base-specific recognition signal in the 5' consensus sequence of rotavirus plus-strand RNAs promotes replication of the double-stranded RNA genome segmentsCryoelectron microscopy structures of rotavirus NSP2-NSP5 and NSP2-RNA complexes: implications for genome replication.The rhesus rotavirus gene encoding VP4 is a major determinant in the pathogenesis of biliary atresia in newborn mice.Rotavirus antagonism of the innate immune responseHistidine triad-like motif of the rotavirus NSP2 octamer mediates both RTPase and NTPase activitiesInteractions among capsid proteins orchestrate rotavirus particle functions.Formation of guanosine(5')tetraphospho(5')adenosine cap structure by an unconventional mRNA capping enzyme of vesicular stomatitis virus.Rotavirus mRNAS are released by transcript-specific channels in the double-layered viral capsidSilencing the alarms: Innate immune antagonism by rotavirus NSP1 and VP3Homologous 2',5'-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity.Structural insights into the coupling of virion assembly and rotavirus replication.Further characterisation of rotavirus cores: Ss(+)RNAs can be packaged in vitro but packaging lacks sequence specificity.Rotavirus Controls Activation of the 2'-5'-Oligoadenylate Synthetase/RNase L Pathway Using at Least Two Distinct Mechanisms.Genome segment 5 of Antheraea mylitta cytoplasmic polyhedrosis virus encodes a bona fide guanylyltransferaseA yeast-based genetic system for functional analysis of viral mRNA capping enzymes.DNA methyltransferase deficiency modifies cancer susceptibility in mice lacking DNA mismatch repair.Deletion of individual mRNA capping genes is unexpectedly not lethal to Candida albicans and results in modified mRNA cap structures.A single amino acid change in the L-polymerase protein of vesicular stomatitis virus completely abolishes viral mRNA cap methylation.Template recognition and formation of initiation complexes by the replicase of a segmented double-stranded RNA virus.Probing the sites of interactions of rotaviral proteins involved in replication.The genome segments of a group D rotavirus possess group A-like conserved termini but encode group-specific proteins.Permissive replication of homologous murine rotavirus in the mouse intestine is primarily regulated by VP4 and NSP1.Conserved sequence motifs for nucleoside triphosphate binding unique to turreted reoviridae members and coltiviruses.Rotavirus nonstructural protein NSP2 self-assembles into octamers that undergo ligand-induced conformational changes.Genome characterization of Turkey Rotavirus G strains from the United States identifies potential recombination events with human Rotavirus B strains.A Novel RNA Phosphorylation State Enables 5' End-Dependent Degradation in Escherichia coli.
P2860
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P2860
Rotavirus open cores catalyze 5'-capping and methylation of exogenous RNA: evidence that VP3 is a methyltransferase.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Rotavirus open cores catalyze ...... at VP3 is a methyltransferase.
@en
Rotavirus open cores catalyze ...... at VP3 is a methyltransferase.
@nl
type
label
Rotavirus open cores catalyze ...... at VP3 is a methyltransferase.
@en
Rotavirus open cores catalyze ...... at VP3 is a methyltransferase.
@nl
prefLabel
Rotavirus open cores catalyze ...... at VP3 is a methyltransferase.
@en
Rotavirus open cores catalyze ...... at VP3 is a methyltransferase.
@nl
P2093
P356
P1433
P1476
Rotavirus open cores catalyze ...... hat VP3 is a methyltransferase
@en
P2093
P304
P356
10.1006/VIRO.1999.0029
P407
P577
1999-12-01T00:00:00Z