Cyclin-dependent kinase 7 (CDK7)-mediated phosphorylation of the CDK9 activation loop promotes P-TEFb assembly with Tat and proviral HIV reactivation.

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Cyclin-dependent kinase 7 (CDK7)-mediated phosphorylation of the CDK9 activation loop promotes P-TEFb assembly with Tat and proviral HIV reactivation.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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2018年學術文章

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name

Cyclin-dependent kinase 7 (CDK ...... and proviral HIV reactivation.

@en

Cyclin-dependent kinase 7

@nl

type

Item

label

Cyclin-dependent kinase 7 (CDK ...... and proviral HIV reactivation.

@en

Cyclin-dependent kinase 7

@nl

prefLabel

Cyclin-dependent kinase 7 (CDK ...... and proviral HIV reactivation.

@en

Cyclin-dependent kinase 7

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P1476

Cyclin-dependent kinase 7 (CDK ...... and proviral HIV reactivation

@en

P2093

Benlian Wang

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Giridharan Gokulrangan

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Jonathan Karn

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Uri Mbonye

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Wuxian Shi

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P2860

The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SK

Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function

Structural basis of cyclin-dependent kinase activation by phosphorylation

The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation

Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stages

Evidence that negative elongation factor represses transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II complex and RNA.

Spt5 cooperates with human immunodeficiency virus type 1 Tat by preventing premature RNA release at terminator sequences

Human immunodeficiency virus type-1 Tat is an integral component of the activated transcription-elongation complex

Crystal structure of HIV-1 Tat complexed with human P-TEFb

Transcriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a cure

P304

10009-10025

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scholarly article

P356

10.1074/JBC.RA117.001347

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P407

English

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P478

293

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Sichun Yang

P577

2018-05-09T00:00:00Z

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P698

29743242

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P921

phosphorylation

P932

6028954

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