An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability.
about
Expression and extracellular release of a functional anti-trypanosome Nanobody® in Sodalis glossinidius, a bacterial symbiont of the tsetse flyProperties, production, and applications of camelid single-domain antibody fragmentsThe production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungiRibosome-inactivating proteins: from plant defense to tumor attackA RhoC biosensor reveals differences in the activation kinetics of RhoA and RhoC in migrating cellsChimeric antigen receptor (CAR)-specific monoclonal antibody to detect CD19-specific T cells in clinical trialsNanobody-aided structure determination of the EpsI:EpsJ pseudopilin heterodimer from Vibrio vulnificusStructure of a single-chain antibody variable domain (Fv) fragment complexed with a carbohydrate antigen at 1.7-A resolutionA monomeric red fluorescent proteinRecognition of E. coli tryptophan synthase by single-chain Fv fragments: comparison of PCR-cloning variants with the parental antibodies.Differentiation of naive cord-blood T cells into CD19-specific cytolytic effectors for posttransplantation adoptive immunotherapy.DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior.Optical Tools To Study the Isoform-Specific Roles of Small GTPases in Immune Cells.Nanobodies as novel agents for cancer therapy.Fusion proteins comprising a Fusarium-specific antibody linked to antifungal peptides protect plants against a fungal pathogen.Fine tuning of the specificity of an anti-progesterone antibody by first and second sphere residue engineering.Optimizing the stability of single-chain proteins by linker length and composition mutagenesis.In vivo tumor targeting and imaging with engineered trivalent antibody fragments containing collagen-derived sequencesA tandem CD19/CD20 CAR lentiviral vector drives on-target and off-target antigen modulation in leukemia cell lines.Recombinant anti-CD20 antibody fragments for small-animal PET imaging of B-cell lymphomas.Bioengineering a unique deimmunized bispecific targeted toxin that simultaneously recognizes human CD22 and CD19 receptors in a mouse model of B-cell metastases.Chimeric antigen receptor-modified T cells derived from defined CD8+ and CD4+ subsets confer superior antitumor reactivity in vivo.A bacteria colony-based screen for optimal linker combinations in genetically encoded biosensorsImproved binding of a bivalent single-chain immunotoxin results in increased efficacy for in vivo T-cell depletion.Adenoviral targeting using genetically incorporated camelid single variable domains.Basis for selection of improved carbohydrate-binding single-chain antibodies from synthetic gene librariesEffective therapeutic approach for head and neck cancer by an engineered minibody targeting the EGFR receptorscFv antibody: principles and clinical applicationNovel avian single-chain fragment variable (scFv) targets dietary gluten and related natural grain prolamins, toxic entities of celiac diseaseSoluble Expression and Characterization of a New scFv Directed to Human CD123.Anti-Amyloid-β Single-Chain Antibody Brain Delivery Via AAV Reduces Amyloid Load But May Increase Cerebral Hemorrhages in an Alzheimer's Disease Mouse ModelThe TWEAK receptor Fn14 is a therapeutic target in melanoma: immunotoxins targeting Fn14 receptor for malignant melanoma treatmentUse of the single cell gel electrophoresis (comet assay) for comparing apoptotic effect of conventional antibodies versus nanobodiesFab-dsFv: A bispecific antibody format with extended serum half-life through albumin binding.Antibody vectors for imaging.Nanobody; an old concept and new vehicle for immunotargeting.Single-chain fragment variable passive immunotherapies for neurodegenerative diseases.Antibody humanization methods - a review and update.Antiferritin single-chain antibody: a functional protein with incomplete folding?Analysis by surface plasmon resonance of the influence of valence on the ligand binding affinity and kinetics of an anti-carbohydrate antibody.
P2860
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P2860
An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
An improved linker for single- ...... nhanced proteolytic stability.
@en
An improved linker for single- ...... nhanced proteolytic stability.
@nl
type
label
An improved linker for single- ...... nhanced proteolytic stability.
@en
An improved linker for single- ...... nhanced proteolytic stability.
@nl
prefLabel
An improved linker for single- ...... nhanced proteolytic stability.
@en
An improved linker for single- ...... nhanced proteolytic stability.
@nl
P2093
P356
P1476
An improved linker for single- ...... nhanced proteolytic stability.
@en
P2093
Hardman KD
Milenic DE
Rollence ML
P304
P356
10.1093/PROTEIN/6.8.989
P577
1993-11-01T00:00:00Z