about
The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas DiseaseIdentification of contractile vacuole proteins in Trypanosoma cruziCD8+ T cells in Trypanosoma cruzi infectionA Heuristic method for assigning a false-discovery rate for protein identifications from Mascot database search resultsHigh throughput selection of effective serodiagnostics for Trypanosoma cruzi infectionIn vitro and in vivo high-throughput assays for the testing of anti-Trypanosoma cruzi compoundsA framework for ontology-based question answering with application to parasite immunologyGenetic immunization with LYT1 or a pool of trans-sialidase genes protects mice from lethal Trypanosoma cruzi infection.Microarray profiling of gene expression during trypomastigote to amastigote transition in Trypanosoma cruzi.Analysis of the Trypanosoma cruzi cyclophilin gene family and identification of Cyclosporin A binding proteins.CD8+ T-Cell responses to Trypanosoma cruzi are highly focused on strain-variant trans-sialidase epitopesThe challenges of Chagas Disease-- grim outlook or glimmer of hope.Evaluation of high efficiency gene knockout strategies for Trypanosoma cruziChromosome level assembly of the hybrid Trypanosoma cruzi genome.The steady-state transcriptome of the four major life-cycle stages of Trypanosoma cruziTrypanoside, anti-tuberculosis, leishmanicidal, and cytotoxic activities of tetrahydrobenzothienopyrimidines.Changes in Trypanosoma cruzi-specific immune responses after treatment: surrogate markers of treatment efficacy.Trypanosoma cruzi-specific immune responses in subjects from endemic areas of Chagas disease of Argentina.Widespread, focal copy number variations (CNV) and whole chromosome aneuploidies in Trypanosoma cruzi strains revealed by array comparative genomic hybridization.Methodological advances in drug discovery for Chagas disease.Generation of Trypanosoma cruzi-specific CD8+ T-cell immunity is unaffected by the absence of type I interferon signaling.Impact of aetiological treatment on conventional and multiplex serology in chronic Chagas disease.Knockout of the dhfr-ts gene in Trypanosoma cruzi generates attenuated parasites able to confer protection against a virulent challenge.Genetic immunization elicits antigen-specific protective immune responses and decreases disease severity in Trypanosoma cruzi infectionA semantic problem solving environment for integrative parasite research: identification of intervention targets for Trypanosoma cruzi.Perpetual expression of PAMPs necessary for optimal immune control and clearance of a persistent pathogenInhibitory receptors are expressed by Trypanosoma cruzi-specific effector T cells and in hearts of subjects with chronic Chagas diseaseChagas disease and the london declaration on neglected tropical diseases.The Trypanosoma cruzi flagellum is discarded via asymmetric cell division following invasion and provides early targets for protective CD8⁺ T cells.Is Chagas disease really the "new HIV/AIDS of the Americas"?A systematic review of high quality diagnostic tests for Chagas diseaseInducible nitric oxide synthase is not essential for control of Trypanosoma cruzi infection in mice.Drug-induced cure drives conversion to a stable and protective CD8+ T central memory response in chronic Chagas disease.Chronic human infection with Trypanosoma cruzi drives CD4+ T cells to immune senescenceCRISPR-Cas9-mediated single-gene and gene family disruption in Trypanosoma cruziPolyfunctional T cell responses in children in early stages of chronic Trypanosoma cruzi infection contrast with monofunctional responses of long-term infected adults.Epigenetic regulation of transcription and virulence in Trypanosoma cruzi by O-linked thymine glucosylation of DNA.Oral exposure to Trypanosoma cruzi elicits a systemic CD8⁺ T cell response and protection against heterotopic challengePerturbed T cell IL-7 receptor signaling in chronic Chagas disease.Chagas disease: a role for autoimmunity?
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P50
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wetenschapper
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հետազոտող
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Rick L Tarleton
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Rick L Tarleton
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Rick L. Tarleton
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Rick L. Tarleton
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Rick L Tarleton
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Rick L Tarleton
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Rick L. Tarleton
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Rick L. Tarleton
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Rick Tarleton
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Rick L Tarleton
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Rick L Tarleton
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Rick L. Tarleton
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Rick L. Tarleton
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