Several generations of chemoenzymatic synthesis of oseltamivir (Tamiflu): evolution of strategy, quest for a process-quality synthesis, and evaluation of efficiency metrics.
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Synthesis, structure and inhibitory activity of a stereoisomer of oseltamivir carboxylateValuable new cyclohexadiene building blocks from cationic η5-iron-carbonyl complexes derived from a microbial arene oxidation product.Palladium-catalyzed carbonylation of halo arene-cis-dihydrodiols to the corresponding carboxylates. Access to compounds unavailable by toluene dioxygenase-mediated dihydroxylation of the corresponding benzoate esters.
P2860
Several generations of chemoenzymatic synthesis of oseltamivir (Tamiflu): evolution of strategy, quest for a process-quality synthesis, and evaluation of efficiency metrics.
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2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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2011年學術文章
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2011年學術文章
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name
Several generations of chemoen ...... luation of efficiency metrics.
@en
Several generations of chemoen ...... luation of efficiency metrics.
@nl
type
label
Several generations of chemoen ...... luation of efficiency metrics.
@en
Several generations of chemoen ...... luation of efficiency metrics.
@nl
prefLabel
Several generations of chemoen ...... luation of efficiency metrics.
@en
Several generations of chemoen ...... luation of efficiency metrics.
@nl
P2093
P356
P1476
Several generations of chemoen ...... luation of efficiency metrics.
@en
P2093
Ales Machara
Bradford Sullivan
David R Adams
Ignacio Carrera
John Andraos
Lukas Werner
Michael Moser
P304
10050-10067
P356
10.1021/JO2018872
P407
P577
2011-11-11T00:00:00Z