Potential new antibiotic sites in the ribosome revealed by deleterious mutations in RNA of the large ribosomal subunit.
about
Antibiotics that target protein synthesisCryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit.Origins and evolution of antibiotic resistanceGenome-guided Investigation of Antibiotic Substances produced by Allosalinactinospora lopnorensis CA15-2(T) from Lop Nor region, China.Selection of small peptides, inhibitors of translation.Identification of distinct thiopeptide-antibiotic precursor lead compounds using translation machinery assaysAssessing functional annotation transfers with inter-species conserved coexpression: application to Plasmodium falciparum.Dynamics of the base of ribosomal A-site finger revealed by molecular dynamics simulations and Cryo-EMProbing translation with small-molecule inhibitorsMutations of highly conserved bases in the peptidyltransferase center induce compensatory rearrangements in yeast ribosomes.Fluorescently labeled ribosomes as a tool for analyzing antibiotic binding.Phylogenetic sequence variations in bacterial rRNA affect species-specific susceptibility to drugs targeting protein synthesis.Analysis of ribosomal inter-subunit sites as targets for complementary oligonucleotides.Ribosome performance is enhanced by a rich cluster of pseudouridines in the A-site finger region of the large subunit.Revealing unique properties of the ribosome using a network based analysis.Random pseuoduridylation in vivo reveals critical region of Escherichia coli 23S rRNA for ribosome assemblyStructural signatures of antibiotic binding sites on the ribosome.NMR characterisation of a highly conserved secondary structural RNA motif of Halobacterium halobium 23S rRNA.
P2860
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P2860
Potential new antibiotic sites in the ribosome revealed by deleterious mutations in RNA of the large ribosomal subunit.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Potential new antibiotic sites ...... f the large ribosomal subunit.
@en
Potential new antibiotic sites ...... f the large ribosomal subunit.
@nl
type
label
Potential new antibiotic sites ...... f the large ribosomal subunit.
@en
Potential new antibiotic sites ...... f the large ribosomal subunit.
@nl
prefLabel
Potential new antibiotic sites ...... f the large ribosomal subunit.
@en
Potential new antibiotic sites ...... f the large ribosomal subunit.
@nl
P2860
P356
P1476
Potential new antibiotic sites ...... f the large ribosomal subunit.
@en
P2093
Alexander S Mankin
P2860
P304
24329-24342
P356
10.1074/JBC.M703106200
P407
P577
2007-06-25T00:00:00Z