The design and synthesis of inhibitors of pantothenate synthetase.

The design and synthesis of inhibitors of pantothenate synthetase.

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http://www.wikidata.org/entity/Q54455232
Biotin Protein Ligase Is a Target for New AntibacterialsInhibition ofMycobacterium tuberculosisPantothenate Synthetase by Analogues of the Reaction IntermediateX-ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoateOptimization of the Interligand Overhauser Effect for Fragment Linking: Application to Inhibitor Discovery against Mycobacterium tuberculosis Pantothenate SynthetaseIntegrated biophysical approach to fragment screening and validation for fragment-based lead discoveryImproved Synthesis of Biotinol-5'-AMP: Implications for Antibacterial Discovery.Reaction intermediate analogues as bisubstrate inhibitors of pantothenate synthetase.Biosynthesis of Pantothenic Acid and Coenzyme A.Adenylating enzymes in Mycobacterium tuberculosis as drug targets.Amino-4-imidazolecarboxamide ribotide directly inhibits coenzyme A biosynthesis in Salmonella enterica.L-2,3-diaminopropionate generates diverse metabolic stresses in Salmonella enterica.Pantothenic acid biosynthesis in the parasite Toxoplasma gondii: a target for chemotherapy.Design, synthesis, and biological evaluation of α-hydroxyacyl-AMS inhibitors of amino acid adenylation enzymes.A comparison of the dynamics of pantothenate synthetase from M. tuberculosis and E. coli: computational studies.Alanine mutation of the catalytic sites of Pantothenate Synthetase causes distinct conformational changes in the ATP binding region.Variation in pantothenate kinase type determines the pantothenamide mode of action and impacts on coenzyme A salvage biosynthesis.Binding of pyrazole-based inhibitors to Mycobacterium tuberculosis pantothenate synthetase: docking and MM-GB(PB)SA analysis
P2860

The design and synthesis of inhibitors of pantothenate synthetase.

Item
http://www.wikidata.org/entity/Q54455232
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
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2006年學術文章
@zh-hant
name
The design and synthesis of inhibitors of pantothenate synthetase.
@en
The design and synthesis of inhibitors of pantothenate synthetase.
@nl
type
label
The design and synthesis of inhibitors of pantothenate synthetase.
@en
The design and synthesis of inhibitors of pantothenate synthetase.
@nl
prefLabel
The design and synthesis of inhibitors of pantothenate synthetase.
@en
The design and synthesis of inhibitors of pantothenate synthetase.
@nl
P1433
P1476
P2093
P304
P31
P356
P433
P478
P50
P577
P698
P356
P1433
P1476
The design and synthesis of inhibitors of pantothenate synthetase.
@en
P2093
P304
P31
P356
P433
P478
P50
P577
P698