Phospholipid dependence and liposome reconstitution of purified hyaluronan synthase.
about
Hyaluronan Synthase: The Mechanism of Initiation at the Reducing End and a Pendulum Model for Polysaccharide Translocation to the Cell ExteriorHyaluronan synthase mediates dye translocation across liposomal membranes.Hyaluronan synthase assembles chitin oligomers with -GlcNAc(α1→)UDP at the reducing end.Hyaluronan accumulation is elevated in cultures of low density lipoprotein receptor-deficient cells and is altered by manipulation of cell cholesterol content.Methyl-beta-cyclodextrin suppresses hyaluronan synthesis by down-regulation of hyaluronan synthase 2 through inhibition of Akt.Heregulin-mediated ErbB2-ERK signaling activates hyaluronan synthases leading to CD44-dependent ovarian tumor cell growth and migration.Hyaluronan synthase assembles hyaluronan on a [GlcNAc(β1,4)]n-GlcNAc(α1→)UDP primer and hyaluronan retains this residual chitin oligomer as a cap at the nonreducing end.
P2860
Q26782588-CE340F97-53BE-4728-A5CC-C738E54C7DF2Q34140787-1BE0524F-D199-4059-8071-969F302DEA5CQ35541734-E8DB05CF-629A-4D8B-A7CA-D9C68BE89364Q37021588-285DC2B6-91B7-431C-8824-CDED42A9F38EQ39700530-58FEDC3A-004D-419F-9A50-7C2310C385F5Q40134433-B959DC62-BAEA-41B8-AB50-84ED6A5C5D08Q46425720-501FE0B6-9290-4ECE-92BE-3B2DB9E0F95E
P2860
Phospholipid dependence and liposome reconstitution of purified hyaluronan synthase.
description
2006 nî lūn-bûn
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年學術文章
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2006年學術文章
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2006年學術文章
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name
Phospholipid dependence and liposome reconstitution of purified hyaluronan synthase.
@en
Phospholipid dependence and liposome reconstitution of purified hyaluronan synthase.
@nl
type
label
Phospholipid dependence and liposome reconstitution of purified hyaluronan synthase.
@en
Phospholipid dependence and liposome reconstitution of purified hyaluronan synthase.
@nl
prefLabel
Phospholipid dependence and liposome reconstitution of purified hyaluronan synthase.
@en
Phospholipid dependence and liposome reconstitution of purified hyaluronan synthase.
@nl
P2093
P2860
P356
P1476
Phospholipid dependence and liposome reconstitution of purified hyaluronan synthase.
@en
P2093
Lindsey C Torres
Paul H Weigel
Zhetcho Kyossev
P2860
P304
36542-36551
P356
10.1074/JBC.M606529200
P407
P577
2006-09-19T00:00:00Z