A critical histidine residue within LIMP-2 mediates pH sensitive binding to its ligand β-glucocerebrosidase.
about
Glucocerebrosidase is shaking up the synucleinopathiesStructure of LIMP-2 provides functional insights with implications for SR-BI and CD36Lysosomal membrane proteins and their central role in physiologyMolecular mechanism of SCARB2-mediated attachment and uncoating of EV71Lysosome sorting of β-glucocerebrosidase by LIMP-2 is targeted by the mannose 6-phosphate receptorLysosomal integral membrane protein-2: a new player in lysosome-related pathologyLIMP-2 expression is critical for β-glucocerebrosidase activity and α-synuclein clearanceThe lysosomal membrane protein SCAV-3 maintains lysosome integrity and adult longevity.A histidine-rich linker region in peptidylglycine α-amidating monooxygenase has the properties of a pH sensor.The LIMP-2/SCARB2 binding motif on acid β-glucosidase: basic and applied implications for Gaucher disease and associated neurodegenerative diseases.Signal-peptide-peptidase-like 2a is required for CD74 intramembrane proteolysis in human B cellsMechanism of Fine-tuning pH Sensors in Proprotein Convertases: IDENTIFICATION OF A pH-SENSING HISTIDINE PAIR IN THE PROPEPTIDE OF PROPROTEIN CONVERTASE 1/3.The tetraspanin CD63 is required for efficient IgE-mediated mast cell degranulation and anaphylaxis.Parkinson's disease: acid-glucocerebrosidase activity and alpha-synuclein clearance.Mannose 6-phosphate-independent Lysosomal Sorting of LIMP-2.Functional characterization of the lysosomal membrane protein TMEM192 in mice.The cellular receptor for enterovirus 71.A role for exocyst in maturation and bactericidal function of staphylococci-containing endothelial cell phagosomes.Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies.Parallel regulation of renin and lysosomal integral membrane protein 2 in renin-producing cells: further evidence for a lysosomal nature of renin secretory vesicles.Lysosomal Proteome and Secretome Analysis Identifies Missorted Enzymes and Their Nondegraded Substrates in Mucolipidosis III Mouse Cells
P2860
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P2860
A critical histidine residue within LIMP-2 mediates pH sensitive binding to its ligand β-glucocerebrosidase.
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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2012年學術文章
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2012年學術文章
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name
A critical histidine residue w ...... s ligand β-glucocerebrosidase.
@en
A critical histidine residue w ...... s ligand β-glucocerebrosidase.
@nl
type
label
A critical histidine residue w ...... s ligand β-glucocerebrosidase.
@en
A critical histidine residue w ...... s ligand β-glucocerebrosidase.
@nl
prefLabel
A critical histidine residue w ...... s ligand β-glucocerebrosidase.
@en
A critical histidine residue w ...... s ligand β-glucocerebrosidase.
@nl
P2093
P1433
P1476
A critical histidine residue w ...... s ligand β-glucocerebrosidase.
@en
P2093
Christina Zachos
Judith Blanz
Paul Saftig
P304
P356
10.1111/J.1600-0854.2012.01372.X
P577
2012-05-15T00:00:00Z