EphB3 suppresses non-small-cell lung cancer metastasis via a PP2A/RACK1/Akt signalling complex.
about
Cytoplasmic targeting of the proto-oncogene SET promotes cell spreading and migrationThe Rac1 hypervariable region in targeting and signaling: a tail of many storiesDiscovery of a Novel Chemotype of Tyrosine Kinase Inhibitors by Fragment-Based Docking and Molecular DynamicsInterplay between chemotaxis and contact inhibition of locomotion determines exploratory cell migrationEphrinB3 blocks EphB3 dependence receptor functions to prevent cell death following traumatic brain injury.Genomics of squamous cell lung cancerPhosphatase: PP2A structural importance, regulation and its aberrant expression in cancer.Attenuation of eph receptor kinase activation in cancer cells by coexpressed ephrin ligandsEph receptors and ephrins as targets for cancer therapy.The important role of the receptor for activated C kinase 1 (RACK1) in nasopharyngeal carcinoma progression.MicroRNA-587 antagonizes 5-FU-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancerEph receptor signaling and ephrinsIonic immune suppression within the tumour microenvironment limits T cell effector function.RACK1 modulates NF-κB activation by interfering with the interaction between TRAF2 and the IKK complex.Ephrin B3 interacts with multiple EphA receptors and drives migration and invasion in non-small cell lung cancerCarbon nanotube electronics--moving forward.The role of EPH receptors in cancer-related epithelial-mesenchymal transitionRACK1, a versatile hub in cancer.Eph receptors and ephrins: therapeutic opportunities.Eph family co-expression patterns define unique clusters predictive of cancer phenotype.Linc00152 Functions as a Competing Endogenous RNA to Confer Oxaliplatin Resistance and Holds Prognostic Values in Colon Cancer.Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung CancerDown-regulation of EphB4 phosphorylation is necessary for esophageal squamous cell carcinoma tumorigenecity.The EphB4 receptor tyrosine kinase promotes lung cancer growth: a potential novel therapeutic target.RACK1 promotes lung cancer cell growth via an MCM7/RACK1/ Akt signaling complex.Biochemical and biophysical characterization of four EphB kinase domains reveals contrasting thermodynamic, kinetic and inhibition profiles.A receptor-interacting protein 1 (RIP1)-independent necrotic death under the control of protein phosphatase PP2A that involves the reorganization of actin cytoskeleton and the action of cofilin-1.Expression of the EPHB4 receptor tyrosine kinase in head and neck and renal malignancies--implications for solid tumors and potential for therapeutic inhibition.EphB3 protein is associated with histological grade and FIGO stage in ovarian serous carcinomas.Formononetin inhibits colon carcinoma cell growth and invasion by microRNA‑149‑mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways.Differential Expression Patterns of Eph Receptors and Ephrin Ligands in Human Cancers.
P2860
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P2860
EphB3 suppresses non-small-cell lung cancer metastasis via a PP2A/RACK1/Akt signalling complex.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
EphB3 suppresses non-small-cel ...... /RACK1/Akt signalling complex.
@en
EphB3 suppresses non-small-cel ...... /RACK1/Akt signalling complex.
@nl
type
label
EphB3 suppresses non-small-cel ...... /RACK1/Akt signalling complex.
@en
EphB3 suppresses non-small-cel ...... /RACK1/Akt signalling complex.
@nl
prefLabel
EphB3 suppresses non-small-cel ...... /RACK1/Akt signalling complex.
@en
EphB3 suppresses non-small-cel ...... /RACK1/Akt signalling complex.
@nl
P2093
P356
P1476
EphB3 suppresses non-small-cel ...... A/RACK1/Akt signalling complex
@en
P2093
Jiang-Sha Zhao
Jing-Jing Li
Jun-Feng Xu
Xiao-Dan Ji
Yin-Qiu Zhu
Yu-Xiong Feng
P2888
P356
10.1038/NCOMMS1675
P407
P50
P577
2012-02-07T00:00:00Z