Phylogenetic and in silico structural analysis of the Parkinson disease-related kinase PINK1.
about
Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of NeuroprotectionThe Parkinson's gene PINK1 regulates cell cycle progression and promotes cancer-associated phenotypesA neo-substrate that amplifies catalytic activity of parkinson's-disease-related kinase PINK1.The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activityPINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondriaCharacterization of PINK1 (PTEN-induced putative kinase 1) mutations associated with Parkinson disease in mammalian cells and DrosophilaPINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson's Disease Pathobiology?Heterozygous PINK1 p.G411S increases risk of Parkinson's disease via a dominant-negative mechanism.Analysis of the regulatory and catalytic domains of PTEN-induced kinase-1 (PINK1).Structural and functional in silico analysis of LRRK2 missense substitutions.Current therapeutic molecules and targets in neurodegenerative diseases based on in silico drug design.PINK1 autophosphorylation is required for ubiquitin recognition.
P2860
Q24339442-B3863521-8612-49E7-8EDD-2A5BC69CE45CQ28587095-FA86C995-6FAD-46BD-AEA2-249274B716C2Q30573927-28FBCBBA-09B1-493B-9B13-ACC11DCD2266Q30846938-12A8BC67-5166-4F18-A645-08009AE95738Q34641661-A906007E-FDE6-4864-ACF2-30D9EC348C93Q36636038-661F0E6F-2BB0-4899-A9F9-CC6C624881E3Q37635610-3CCCCAD7-668B-4270-BF8F-A2224C74A4B5Q37736984-F9A5065F-AC49-438B-922D-674944272704Q38014338-2F0F76AB-76CB-4C5D-8280-AB8B04DC7CC7Q45143202-84CB96A6-BEC9-4A82-B920-F3E103173010Q52654614-5611FD5E-9320-487A-84C8-4E6FC243E483Q52687770-E1FD37E2-8320-4FEB-9F7D-F64A18AC409B
P2860
Phylogenetic and in silico structural analysis of the Parkinson disease-related kinase PINK1.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Phylogenetic and in silico str ...... disease-related kinase PINK1.
@en
Phylogenetic and in silico str ...... disease-related kinase PINK1.
@nl
type
label
Phylogenetic and in silico str ...... disease-related kinase PINK1.
@en
Phylogenetic and in silico str ...... disease-related kinase PINK1.
@nl
prefLabel
Phylogenetic and in silico str ...... disease-related kinase PINK1.
@en
Phylogenetic and in silico str ...... disease-related kinase PINK1.
@nl
P2093
P2860
P356
P1433
P1476
Phylogenetic and in silico str ...... disease-related kinase PINK1.
@en
P2093
Fernando Cardona
Hernán Dopazo
Jose Vicente Sánchez-Mut
P2860
P304
P356
10.1002/HUMU.21444
P577
2011-04-01T00:00:00Z