Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling.
about
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organizationAbi-1 forms an epidermal growth factor-inducible complex with Cbl: role in receptor endocytosisCooperative interactions at the SLP-76 complex are critical for actin polymerizationRegulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contextsWASp family verprolin-homologous protein-2 (WAVE2) and Wiskott-Aldrich syndrome protein (WASp) engage in distinct downstream signaling interactions at the T cell antigen receptor siteAcute inhibition of selected membrane-proximal mouse T cell receptor signaling by mitochondrial antagonistsA novel flow cytometric high throughput assay for a systematic study on molecular mechanisms underlying T cell receptor-mediated integrin activationA point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic protein 1 in lymphopoiesis and innate immunityWASH knockout T cells demonstrate defective receptor trafficking, proliferation, and effector functionThe N terminus of SKAP55 enables T cell adhesion to TCR and integrin ligands via distinct mechanisms.Functional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics.The c-Abl tyrosine kinase regulates actin remodeling at the immune synapseCyfip1 is a putative invasion suppressor in epithelial cancers.Specific patterns of Cdc42 activity are related to distinct elements of T cell polarizationFunctional cooperation between the proteins Nck and ADAP is fundamental for actin reorganization.Computational spatiotemporal analysis identifies WAVE2 and cofilin as joint regulators of costimulation-mediated T cell actin dynamicsAbl kinase inhibits the engulfment of apoptotic [corrected] cells in Caenorhabditis elegansWAVE1 regulates P-glycoprotein expression via Ezrin in leukemia cells.Expression of Abelson interactor 1 (Abi1) correlates with inflammation, KRAS mutation and adenomatous change during colonic carcinogenesis.Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the alpha4 integrin.Impairment of immunological synapse formation in adaptively tolerant T cellsRegulation of cytoskeletal dynamics at the immune synapse: new stars join the actin troupeLoss of Wave1 gene defines a subtype of lethal prostate cancerHem-1: putting the "WAVE" into actin polymerization during an immune response.Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells.T Cell Motility as Modulator of Interactions with Dendritic CellsThe emerging role of protein kinase Cθ in cytoskeletal signaling.A new role for cofilin in retinal neovascularization.Abi1 gene silencing by short hairpin RNA impairs Bcr-Abl-induced cell adhesion and migration in vitro and leukemogenesis in vivo.Adhesions ring: a structural comparison between podosomes and the immune synapse.Calcium influx through CRAC channels controls actin organization and dynamics at the immune synapse.Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/TxkAbl tyrosine kinases in T-cell signalingLipid-based patterning of the immunological synapseHIV-1 at the immunological and T-lymphocytic virological synapse.Coordinate control of cytoskeletal remodeling and calcium mobilization during T-cell activationAnnular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse.Upregulated WAVE3 expression is essential for TGF-β-mediated EMT and metastasis of triple-negative breast cancer cells.A conformational change within the WAVE2 complex regulates its degradation following cellular activationMultiple pathways leading from the T-cell antigen receptor to the actin cytoskeleton network.
P2860
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P2860
Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Role for the Abi/wave protein ...... n and cytoskeletal remodeling.
@en
Role for the Abi/wave protein ...... n and cytoskeletal remodeling.
@nl
type
label
Role for the Abi/wave protein ...... n and cytoskeletal remodeling.
@en
Role for the Abi/wave protein ...... n and cytoskeletal remodeling.
@nl
prefLabel
Role for the Abi/wave protein ...... n and cytoskeletal remodeling.
@en
Role for the Abi/wave protein ...... n and cytoskeletal remodeling.
@nl
P2093
P50
P1433
P1476
Role for the Abi/wave protein ...... on and cytoskeletal remodeling
@en
P2093
Ann Marie Pendergast
Colleen Ring
Jing Jin Gu
Patricia A Zipfel
P356
10.1016/J.CUB.2005.12.024
P407
P577
2006-01-01T00:00:00Z