Potent cross-reactive immune response against the wild-type and drug-resistant forms of HIV reverse transcriptase after the chimeric gene immunization.
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Regulation of Immunogen Processing: Signal Sequences and Their Application for the New Generation of DNA-VaccinesAddressing viral resistance through vaccinesOxidative stress induced by HIV-1 reverse transcriptase modulates the enzyme's performance in gene immunization.Fusion to the Lysosome Targeting Signal of the Invariant Chain Alters the Processing and Enhances the Immunogenicity of HIV-1 Reverse TranscriptaseLuciferase Expression Allows Bioluminescence Imaging But Imposes Limitations on the Orthotopic Mouse (4T1) Model of Breast Cancer.Fusion to Flaviviral Leader Peptide Targets HIV-1 Reverse Transcriptase for Secretion and Reduces Its Enzymatic Activity and Ability to Induce Oxidative Stress but Has No Major Effects on Its Immunogenic Performance in DNA-Immunized Mice.Codon optimization and improved delivery/immunization regimen enhance the immune response against wild-type and drug-resistant HIV-1 reverse transcriptase, preserving its Th2-polarity.DNA immunization site determines the level of gene expression and the magnitude, but not the type of the induced immune response.
P2860
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P2860
Potent cross-reactive immune response against the wild-type and drug-resistant forms of HIV reverse transcriptase after the chimeric gene immunization.
description
2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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name
Potent cross-reactive immune r ...... he chimeric gene immunization.
@en
Potent cross-reactive immune r ...... he chimeric gene immunization.
@nl
type
label
Potent cross-reactive immune r ...... he chimeric gene immunization.
@en
Potent cross-reactive immune r ...... he chimeric gene immunization.
@nl
prefLabel
Potent cross-reactive immune r ...... he chimeric gene immunization.
@en
Potent cross-reactive immune r ...... he chimeric gene immunization.
@nl
P2093
P50
P1433
P1476
Potent cross-reactive immune r ...... he chimeric gene immunization.
@en
P2093
Alexander Chernousov
Andreas Boberg
Elizaveta Starodubova
Maria G Isaguliants
Marina Litvina
Natalia Petrakova
Oleg Latyshev
Vadim Karpov
Yulia Kuzmenko
P304
P356
10.1016/J.VACCINE.2009.10.098
P407
P577
2010-02-01T00:00:00Z