FGF-23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa.
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SLC34A3 mutations in patients with hereditary hypophosphatemic rickets with hypercalciuria predict a key role for the sodium-phosphate cotransporter NaPi-IIc in maintaining phosphate homeostasisHereditary hypophosphatemic rickets with hypercalciuria is caused by mutations in the sodium-phosphate cotransporter gene SLC34A3.FGF23-mediated regulation of systemic phosphate homeostasis: is Klotho an essential player?Miscellaneous non-inflammatory musculoskeletal conditions. Hyperphosphatemic familial tumoral calcinosis (FGF23, GALNT3 and αKlotho)Vitamin D and the kidneyFGF23 and Phosphate Wasting DisordersRegulation and function of the FGF23/klotho endocrine pathwaysCardiovascular Risk Factors and Chronic Kidney Disease-FGF23: A Key Molecule in the Cardiovascular DiseaseDeletion of PTH rescues skeletal abnormalities and high osteopontin levels in Klotho-/- miceA potential link between phosphate and aging--lessons from Klotho-deficient miceFibroblast Growth Factor-23-A Potential Uremic ToxinDysregulation of phosphate metabolism and conditions associated with phosphate toxicityRecent advances in the renal-skeletal-gut axis that controls phosphate homeostasisGenetic evidence of serum phosphate-independent functions of FGF-23 on boneHomozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient miceRelationship between Fibroblast Growth Factor 23 and Biochemical and Bone Histomorphometric Alterations in a Chronic Kidney Disease Rat Model Undergoing ParathyroidectomyThe parathyroid is a target organ for FGF23 in ratsFGF23 deficiency leads to mixed hearing loss and middle ear malformation in mice.α-Klotho expression determines nitric oxide synthesis in response to FGF-23 in human aortic endothelial cellsMineral metabolism and aging: the fibroblast growth factor 23 enigma.FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1.Analysis of the biochemical mechanisms for the endocrine actions of fibroblast growth factor-23Association of serum levels of FGF23 and α-Klotho with glomerular filtration rate and proteinuria among cardiac patients.Relationship between Fibroblast Growth Factor-23 and Mineral Metabolism in Chronic Kidney DiseasePharmacokinetics and pharmacodynamics of a human monoclonal anti-FGF23 antibody (KRN23) in the first multiple ascending-dose trial treating adults with X-linked hypophosphatemia.Cellular ATP synthesis mediated by type III sodium-dependent phosphate transporter Pit-1 is critical to chondrogenesisRecent advances in renal phosphate handling.Altered renal FGF23-mediated activity involving MAPK and Wnt: effects of the Hyp mutationCalcium-deficiency assessment and biomarker identification by an integrated urinary metabonomics analysis.Initial FGF23-mediated signaling occurs in the distal convoluted tubuleFGF-23 regulates CYP27B1 transcription in the kidney and in extra-renal tissues.Molecular regulation of phosphate metabolism by fibroblast growth factor-23-klotho systemEvaluation of a method for fibroblast growth factor-23: a novel biomarker of adverse outcomes in patients with renal disease.FGF-23/Klotho signaling is not essential for the phosphaturic and anabolic functions of PTH.Chronic high fructose intake reduces serum 1,25 (OH)2D3 levels in calcium-sufficient rodents.Regulation of phosphate transport by fibroblast growth factor 23 (FGF23): implications for disorders of phosphate metabolism.Parathyroid hormone receptor signaling in osteocytes increases the expression of fibroblast growth factor-23 in vitro and in vivoFibroblast growth factor 23 regulates renal 1,25-dihydroxyvitamin D and phosphate metabolism via the MAP kinase signaling pathway in Hyp miceGenetic ablation of vitamin D activation pathway reverses biochemical and skeletal anomalies in Fgf-23-null animals.FGF23 in skeletal modeling and remodeling.
P2860
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P2860
FGF-23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
FGF-23 transgenic mice demonst ...... sphate cotransporter type IIa.
@en
FGF-23 transgenic mice demonst ...... sphate cotransporter type IIa.
@nl
type
label
FGF-23 transgenic mice demonst ...... sphate cotransporter type IIa.
@en
FGF-23 transgenic mice demonst ...... sphate cotransporter type IIa.
@nl
prefLabel
FGF-23 transgenic mice demonst ...... sphate cotransporter type IIa.
@en
FGF-23 transgenic mice demonst ...... sphate cotransporter type IIa.
@nl
P2093
P1476
FGF-23 transgenic mice demonst ...... sphate cotransporter type IIa.
@en
P2093
Hisashi Hasegawa
Itaru Urakawa
Rieko Hino
Seiji Fukumoto
Takashi Shimada
Takashi Yoneya
Takeyoshi Yamashita
Toshiro Fujita
Yasuhiro Takeuchi
Yuji Yamazaki
P304
P356
10.1016/J.BBRC.2003.12.102
P407
P577
2004-02-01T00:00:00Z