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PP2A phosphatase suppresses function of the mesenchymal invasion regulator NEDD9Proteome analysis of vinca alkaloid response and resistance in acute lymphoblastic leukemia reveals novel cytoskeletal alterations.Proteomic analysis reveals a novel role for the actin cytoskeleton in vincristine resistant childhood leukemia--an in vivo study.Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression.Identification of novel diagnostic biomarkers for asthma and chronic obstructive pulmonary disease.Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons.Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT+ cancersEssential role of protein phosphatase 2A in metaphase II arrest and activation of mouse eggs shown by okadaic acid, dominant negative protein phosphatase 2A, and FTY720.Clinical proteomics: present and future prospects.Drug resistance mechanisms in cancer cells: a proteomics perspective.Basal protein phosphatase 2A activity restrains cytokine expression: role for MAPKs and tristetraprolinFTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia.A systematic evaluation of the safety and toxicity of fingolimod for its potential use in the treatment of acute myeloid leukaemia.Improving the targeting of tubulin-binding agents: lessons from drug resistance studies.The phosphorylated form of FTY720 activates PP2A, represses inflammation and is devoid of S1P agonism in A549 lung epithelial cells.Expression of renin-angiotensin system (RAS) components in endometrial cancer.Controlling the cell cycle: the role of calcium/calmodulin-stimulated protein kinases I and II.Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia.Activating protein phosphatase 2A (PP2A) enhances tristetraprolin (TTP) anti-inflammatory function in A549 lung epithelial cells.TLR2 ligation induces corticosteroid insensitivity in A549 lung epithelial cells: Anti-inflammatory impact of PP2A activators.Involvement of vacuolar H(+)-ATPase in killing of human melanoma cells by the sphingosine kinase analogue FTY720.PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity.Dephosphorylation of CaMKII at T253 controls the metaphase-anaphase transition.Harnessing the power of proteomics for identification of oncogenic, druggable signalling pathways in cancer.Salmeterol attenuates chemotactic responses in rhinovirus-induced exacerbation of allergic airways disease by modulating protein phosphatase 2A.Protein phosphatase 2A carboxymethylation and regulatory B subunits differentially regulate mast cell degranulation.Regulation of CaMKII by phospho-Thr253 or phospho-Thr286 sensitive targeting alters cellular function.A role for altered microtubule polymer levels in vincristine resistance of childhood acute lymphoblastic leukemia xenografts.Alterations in gamma-actin and tubulin-targeted drug resistance in childhood leukemia.Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors.Peripheral Lipopolysaccharide Challenge Induces Long-Term Changes in Tyrosine Hydroxylase Regulation in the Adrenal Medulla.The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity.Functional importance of PP2A regulatory subunit loss in breast cancer.Targeting PP2A and proteasome activity ameliorates features of allergic airway disease in mice.Theophylline Represses IL-8 Secretion from Airway Smooth Muscle Cells Independently of Phosphodiesterase Inhibition. Novel Role as a Protein Phosphatase 2A Activator.Cell-Free DNA Blood Collection Tubes Are Appropriate for Clinical Proteomics: A Demonstration in Colorectal Cancer.Targeting Oncogenic Signaling in Mutant FLT3 Acute Myeloid Leukemia: The Path to Least ResistanceThe microbial proteome database--an automated laboratory catalogue for monitoring protein expression in bacteriaThe proteomics of ageingNeuronal-associated microtubule proteins class III beta-tubulin and MAP2c in neuroblastoma: role in resistance to microtubule-targeted drugs
P50
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P50
description
hulumtuese
@sq
researcher
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wetenschapper
@nl
հետազոտող
@hy
name
Nicole M Verrills
@ast
Nicole M Verrills
@en
Nicole M Verrills
@es
Nicole M Verrills
@nl
Nicole M Verrills
@sl
type
label
Nicole M Verrills
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Nicole M Verrills
@en
Nicole M Verrills
@es
Nicole M Verrills
@nl
Nicole M Verrills
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prefLabel
Nicole M Verrills
@ast
Nicole M Verrills
@en
Nicole M Verrills
@es
Nicole M Verrills
@nl
Nicole M Verrills
@sl
P106
P21
P31
P496
0000-0002-7894-0137