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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalkHypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumorsBCL-3 expression promotes colorectal tumorigenesis through activation of AKT signallingLGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE2: implications for targeting adenoma stem cells with NSAIDs.The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment.BAG-1 suppresses expression of the key regulatory cytokine transforming growth factor β (TGF-β1) in colorectal tumour cells.LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma.Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells.β-catenin negatively regulates expression of the prostaglandin transporter PGT in the normal intestinal epithelium and colorectal tumour cells: a role in the chemopreventive efficacy of aspirin?β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells.HGF/Met signalling promotes PGE(2) biogenesis via regulation of COX-2 and 15-PGDH expression in colorectal cancer cells.The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells.The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2.Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways.The proapoptotic BH3-only protein Bim is downregulated in a subset of colorectal cancers and is repressed by antiapoptotic COX-2/PGE(2) signalling in colorectal adenoma cells.Circulating prostaglandins as biomarkers for colorectal cancer?Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells.Colon tumour cells increase PGE(2) by regulating COX-2 and 15-PGDH to promote survival during the microenvironmental stress of glucose deprivation.LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity.Wnt Signalling Drives Context-Dependent Differentiation or Proliferation in Neuroblastoma.Optimized delivery of siRNA into 3D tumor spheroid cultures in situ.Live imaging of wound angiogenesis reveals macrophage orchestrated vessel sprouting and regression.Cancer cell adaptation to hypoxia involves a HIF‐GPRC5A‐YAP axisBCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cellsLEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cellsWnt signalling is a major determinant of neuroblastoma cell lineages: Supplementary Figures 1-3Wnt signalling drives context-dependent differentiation or proliferation in neuroblastomaCannabinoids and cancer: potential for colorectal cancer therapy: Table 1p16INK4a polymorphism: associations with tumour progression in patients with sporadic colorectal cancerWnt Signaling Is a Major Determinant of Neuroblastoma Cell LineagesGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)A Wnt-BMP4 Signaling Axis Induces MSX and NOTCH Proteins and Promotes Growth Suppression and Differentiation in Neuroblastoma
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Alexander Greenhough
@ast
Alexander Greenhough
@en
Alexander Greenhough
@es
Alexander Greenhough
@nl
type
label
Alexander Greenhough
@ast
Alexander Greenhough
@en
Alexander Greenhough
@es
Alexander Greenhough
@nl
prefLabel
Alexander Greenhough
@ast
Alexander Greenhough
@en
Alexander Greenhough
@es
Alexander Greenhough
@nl
P106
P1153
22979764400
P21
P31
P496
0000-0002-8306-811X